Antimicrobial resistance of Pseudomonas aeruginosa: navigating clinical impacts, current resistance trends, and innovations in breaking therapies

A Elfadadny, RF Ragab, M AlHarbi, F Badshah… - Frontiers in …, 2024 - frontiersin.org
Pseudomonas aeruginosa, a Gram-negative bacterium, is recognized for its adaptability and
opportunistic nature. It poses a substantial challenge in clinical settings due to its …

[HTML][HTML] ESKAPE pathogens and associated quorum sensing systems–New targets for novel antimicrobials development

AE Christiana, C Theolyn, WN S'thebe, D Yamkela… - Health Sciences …, 2024 - Elsevier
Globally, antimicrobial (AMR) or multi-drug resistance (MDR) constitutes a current health
challenge that is predicted to cause increased infections rates with adverse socioeconomic …

Green synthesis and characterization of silver nanoparticles from Ducrosia flabellifolia Boiss. aqueous extract: Anti-quorum sensing screening and antimicrobial …

M Snoussi, RH Lajimi, S Latif, WS Hamadou… - Cellular and Molecular …, 2024 - cellmolbiol.org
Biosynthesis of silver nanoparticles using natural compounds derived from plant kingdom is
currently used as safe and low-cost technique for nanoparticles synthesis with important …

Multifaceted toxicity assessment of Au, Ag, and TiO2 nanoparticles synthesized by quorum quenching bacterium Salmonella bongori: Impact on bacterial pathogens …

B Govindasamy - Process Safety and Environmental Protection, 2024 - Elsevier
The present study pertained to evaluate biological properties of the nanoparticles
synthesised using quorum quenching-QQ Salmonella bongori-SB. The QQ potential of SB …

[HTML][HTML] Myrtus communis leaf compounds as novel inhibitors of quorum sensing-regulated virulence factors and biofilm formation: in vitro and in silico investigations

N Khadraoui, R Essid, B Damergi, N Fares, D Gharbi… - Biofilm, 2024 - Elsevier
Antibiotic resistance of the Gram-negative bacterium Pseudomonas aeruginosa and its
ability to form biofilm through the Quorum Sensing (QS) mechanism are important …

Phytogenic zinc oxide nanoparticles (ZnO NPs) using Solanum xanthocarpum fruit extract: Its evaluation of photocatalytic activity, molecular docking and biomedical …

J Jayaprakash, S Paramasivam, C Jayaseelan… - Inorganic Chemistry …, 2024 - Elsevier
This study presents an eco-friendly synthesis of Zinc Oxide nanoparticles (ZnO NPs) using
fruit extract from Solanum xanthocarpum (SX). TEM analysis revealed that the synthesized …

Metal and Metal Oxide Nanoparticles: Computational Analysis of Their Interactions and Antibacterial Activities Against Pseudomonas aeruginosa

BE Sadoq, S Mujwar, M Sadoq, Y Boulaamane… - BioNanoScience, 2025 - Springer
The effectiveness of antibiotics against Pseudomonas aeruginosa (P. aeruginosa) infections
is limited by inherent antimicrobial resistance, prompting researchers to seek advanced and …

Chitosan–Aspirin Combination Inhibits Quorum-Sensing Synthases (lasI and rhlI) in Pseudomonas aeruginosa

MSEM Badawy, OKM Riad, MF Harras, R Binsuwaidan… - Life, 2024 - mdpi.com
Background: Quorum sensing (QS) controls the virulence of P. aeruginosa. This study aims
to determine the anti-QS activity of aspirin alone and in combination with chitosan to reach …

Green Synthesis and Characterization of Apple Peel‐Derived Selenium Nanoparticles for Anti‐Fungal Activity and Effects of MexA Gene Expression on Efflux Pumps …

ME Ahmed, GM Sulaiman, BA Hasoon… - Applied …, 2024 - Wiley Online Library
ABSTRACT Selenium nanoparticles (Se‐NPs) were produced adopting an environmentally
benign green synthetic approach from the waste biomaterial obtained from the apple peel …

[HTML][HTML] Identification of anti-pathogenic activity among in silico predicted small-molecule inhibitors of Pseudomonas aeruginosa LasR or nitric oxide reductase (NOR)

G Gajera, N Henriksen, B Cox, V Kothari - Drug Target Insights, 2023 - ncbi.nlm.nih.gov
Methods: In silico identification of potential LasR or NOR inhibitors was attempted through a
virtual screening platform AtomNet® to obtain a final subset of< 100 top scoring compounds …