One quarter of the global population is estimated to have nonalcoholic fatty liver disease
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …

Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

PURPOSE We evaluated the efficacy and safety of pembrolizumab in patients from Asia with
previously treated advanced hepatocellular carcinoma (HCC). METHODS In a double-blind …

Liver cancer is one of the leading causes of cancer-related mortality around the world.
Hepatocellular carcinoma (HCC) is the primary cancer of the liver, accounting for the …

Background Personalized immunotherapy utilizing cancer vaccines tailored to the tumors of
individual patients holds promise for tumors with high genetic heterogeneity, potentially …

This Review presents current epidemiological trends of the most common liver diseases in
Asia–Pacific countries. Hepatitis B virus (HBV) remains the primary cause of cirrhosis; …

Hepatocellular carcinoma (HCC) is the predominant primary liver cancer in many countries
and is the third most common cause of cancer-related death in the Asia-Pacific region. The …

Importance The presence of microvascular invasion (MVI) decreases surgical outcomes of
hepatocellular carcinoma (HCC). An accurate preoperative prediction of MVI can help …

Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic
instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration …

Hepatocellular Carcinoma (HCC) is a highly aggressive cancer with mortality running
parallel to its incidence and has limited therapeutic options. Chronic liver inflammation and …