Mucosal vaccines: novel strategies and applications for the control of pathogens and tumors at mucosal sites
M Nizard, MO Diniz, H Roussel, T Tran… - Human vaccines & …, 2014 - Taylor & Francis
The mucosal immune system displays several adaptations reflecting the exposure to the
external environment. The efficient induction of mucosal immune responses also requires …
external environment. The efficient induction of mucosal immune responses also requires …
Cholera toxin, LT-I, LT-IIa and LT-IIb: the critical role of ganglioside binding in immunomodulation by type I and type II heat-labile enterotoxins
TD Connell - Expert review of vaccines, 2007 - Taylor & Francis
The heat-labile enterotoxins expressed by Vibrio cholerae (cholera toxin) and Escherichia
coli (LT-I, LT-IIa and LT-IIb) are potent systemic and mucosal adjuvants. Coadministration of …
coli (LT-I, LT-IIa and LT-IIb) are potent systemic and mucosal adjuvants. Coadministration of …
Recombinant Helicobacter pylori Vaccine Delivery Vehicle: A Promising Tool to Treat Infections and Combat Antimicrobial Resistance
Antimicrobial resistance (AMR) has become a global public health threat. Experts agree that
unless proper actions are taken, the number of deaths due to AMR will increase. Many …
unless proper actions are taken, the number of deaths due to AMR will increase. Many …
Recent advances in nontoxic Escherichia coli heat-labile toxin and its derivative adjuvants
Y Ma - Expert review of vaccines, 2016 - Taylor & Francis
Introduction: The nontoxic heat-labile enterotoxin (LT) of Escherichia coli and the B subunit
of LT (LTB) have been extensively studied as potent vaccine adjuvants. Areas covered: This …
of LT (LTB) have been extensively studied as potent vaccine adjuvants. Areas covered: This …
Recombination among protein II genes of Neisseria gonorrhoeae generates new coding sequences and increases structural variability in the protein II family
TD Connell, WJ Black, TH Kawula… - Molecular …, 1988 - Wiley Online Library
Summary Expression of Neisseria gonorrhoeae Protein II (P. II) is subject to phase variation
and antigenic variation. The P. II proteins made by one strain possess both unique and …
and antigenic variation. The P. II proteins made by one strain possess both unique and …
Type II heat-labile enterotoxins: structure, function, and immunomodulatory properties
G Hajishengallis, TD Connell - Veterinary immunology and …, 2013 - Elsevier
The heat-labile enterotoxins (HLTs) of Escherichia coli and Vibrio cholerae are classified
into two major types on the basis of genetic, biochemical, and immunological properties …
into two major types on the basis of genetic, biochemical, and immunological properties …
LT-IIc, a New Member of the Type II Heat-Labile Enterotoxin Family Encoded by an Escherichia coli Strain Obtained from a Nonmammalian Host
HF Nawar, ND King-Lyons, JC Hu, RC Pasek… - Infection and …, 2010 - Am Soc Microbiol
Two families of bacterial heat-labile enterotoxins (HLTs) have been described: the type I
HLTs are comprised of cholera toxin (CT) of Vibrio cholerae, LT-I of Escherichia coli, and …
HLTs are comprised of cholera toxin (CT) of Vibrio cholerae, LT-I of Escherichia coli, and …
Protection Against Helicobacter pylori Infection in Mongolian Gerbil by Intragastric or Intramuscular Administration of H. pylori Multicomponent Vaccine
C Wu, Y Shi, H Guo, WY Zou, G Guo, QH Xie… - …, 2008 - Wiley Online Library
Abstract Background: Development of Helicobacter pylori vaccine would be a new effective
strategy for prevention and treatment of H. pylori infection. Recombinant H. pylori vaccine …
strategy for prevention and treatment of H. pylori infection. Recombinant H. pylori vaccine …
Mucosal vaccination against bacterial respiratory infections
U Baumann - Expert Review of Vaccines, 2008 - Taylor & Francis
Mucosal vaccination offers attractive advantages to conventional systemic vaccination, such
as higher levels of antibodies and protection at the airway surface. This review gives an …
as higher levels of antibodies and protection at the airway surface. This review gives an …
Immunogenicity and In Vitro and In Vivo Protective Effects of Antibodies Targeting a Recombinant Form of the Streptococcus mutans P1 Surface Protein
MT Batista, RD Souza, EL Ferreira… - Infection and …, 2014 - Am Soc Microbiol
Streptococcus mutans is a major etiologic agent of dental caries, a prevalent worldwide
infectious disease and a serious public health concern. The surface-localized S. mutans P1 …
infectious disease and a serious public health concern. The surface-localized S. mutans P1 …