Chemical cross-linking of proteins coupled with mass spectrometry analysis (CXMS) is
widely used to study protein-protein interactions (PPI), protein structures, and even protein …

Background Caenorhabditis elegans is a powerful model organism for probing many
biological processes including host-pathogen interactions with bacteria and fungi. The …

Type 2 diabetes is a chronic disease and hyperglycemia is important in the pathogenesis of
diabetic complications. Exposure of LO2 cells to high glucose resulted in cellular glucose …

In several species, Piwi/piRNA genome silencing defects cause immediate sterility that
correlates with transposon expression and transposon-induced genomic instability. In C …

Hsp90 is a molecular chaperone involved in the regulation and maturation of kinases and
transcription factors. In Caenorhabditis elegans, it contributes to the development of fertility …

Cry6A represents a novel family of nematicidal crystal proteins from Bacillus thuringiensis. It
has distinctive architecture as well as mechanism of action from Cry5B, a highly focused …

Background Venom-expressed sphingomyelinase D/phospholipase D (SMase D/PLD)
enzymes evolved from the ubiquitous glycerophosphoryl diester phosphodiesterases …

Worldwide, more than 1 billion people are affected by infestations with soil-transmitted
helminths and also in veterinary medicine helminthiases are a severe threat to livestock due …

Withania somnifera is among the most widely prescribed medicinal plants in traditional
Indian medicine. Hydroalcoholic extract of the roots of this plant was investigated for its …

Humans exhibit considerable tolerance for Copy Number Variations (CNVs). A recent study
found that on average, humans have more than 30 genes as CNVs. Therefore, it is …