[HTML][HTML] Update on the applications and limitations of alpha-fetoprotein for hepatocellular carcinoma

H Hanif, MJ Ali, AT Susheela, IW Khan… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Alpha-fetoprotein (AFP) is an oncofetal glycoprotein that has been used as a tumor marker
for hepatocellular carcinoma (HCC) in combination with ultrasound and other imaging …

A comprehensive overview of liquid biopsy applications in pediatric solid tumors

FW Janssen, NSM Lak, CY Janda, LA Kester… - NPJ precision …, 2024 - nature.com
Liquid biopsies are emerging as an alternative source for pediatric cancer biomarkers with
potential applications during all stages of patient care, from diagnosis to long-term follow-up …

Integrated plasma metabolomics and lipidomics profiling highlights distinctive signature of hepatocellular carcinoma in HCV patients

V Caponigro, AL Tornesello, F Merciai… - Journal of Translational …, 2023 - Springer
Background Early diagnosis of hepatocellular carcinoma (HCC) is essential towards the
improvement of prognosis and patient survival. Circulating markers such as α-fetoprotein …

A comparison of clinical pathologic characteristics between alpha-fetoprotein negative and positive hepatocellular carcinoma patients from Eastern and Southern …

X Chi, L Jiang, Y Yuan, X Huang, X Yang… - BMC …, 2022 - Springer
Background Alpha-fetoprotein (AFP) is a biomarker used in clinical management of
hepatocellular carcinoma (HCC), however, approximately 40% of HCC patients do not …

An insight into the role of alpha-fetoprotein (AFP) in the development and progression of hepatocellular carcinoma

SS Samban, A Hari, B Nair, AR Kumar, BS Meyer… - Molecular …, 2024 - Springer
Hepatocellular carcinoma (HCC) is the primary malignancy of hepatocytes and the second
most common cause of cancer-related mortality across the globe. Despite significant …

Golgi protein 73 versus alpha-fetoprotein as a new biomarker in early diagnosis of hepatocellular carcinoma

OM Ali, HA El Amin, YL Sharkawy… - … Journal of General …, 2020 - Taylor & Francis
Background Screening of early hepatocellular carcinoma (HCC) diagnosis is the greatest
challenge for hepatologists. Alpha-fetoprotein (AFP) is the most common non-invasive …

Gamma glutamyl transpeptidase as a prognostic biomarker in hepatocellular cancer patients especially with> 5 cm tumors, treated by liver transplantation

V Ince, BI Carr, HG Bag, C Koc, S Usta… - … journal of biological …, 2020 - journals.sagepub.com
Background Serum AFP levels are typically elevated in less than 50% of hepatocellular
cancer (HCC) patients. Gamma-glutamyl transpeptidase (GGT) levels have been suggested …

Cross-linked multimeric pro-peptides of Type III collagen (PC3X) in hepatocellular carcinoma–a biomarker that provides additional prognostic value in AFP positive …

C Jensen, S Holm Nielsen, M Eslam… - Journal of …, 2020 - Taylor & Francis
Purpose Non-invasive biomarkers for diagnosing and prognosing hepatocellular carcinoma
(HCC) are urgently needed. Cirrhosis is present in 80–90% of HCC patients. Cirrhosis is …

Serum levels of inflammatory markers CRP, ESR and albumin in relation to survival for patients with hepatocellular carcinoma

H Akkiz, BI Carr, HG Bag… - … journal of clinical …, 2021 - Wiley Online Library
Introduction Hepatocellular carcinoma is associated with several chronic inflammatory
conditions. It is increasingly understood that the inflammation may be part of the …

A gene expression signature to select hepatocellular carcinoma patients for liver transplantation

H Pinto-Marques, J Cardoso, S Silva, JL Neto… - Annals of …, 2022 - journals.lww.com
Objective: To propose a new decision algorithm combining biomarkers measured in a tumor
biopsy with clinical variables, to predict recurrence after liver transplantation (LT) …