Cerebral blood flow (CBF) regulation is essential for normal brain function. The mammalian
brain has evolved a unique mechanism for CBF control known as neurovascular coupling …

The NINCDS–ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the
prevailing diagnostic standards in research; however, they have now fallen behind the …

Objective: Primary progressive aphasia (PPA) is characterized by isolated decline in
language functions. Semantic dementia and progressive nonfluent aphasia are accepted …

Chronic cerebral hypoperfusion has been associated with cognitive decline in aging and
Alzheimer's disease. Moreover, the pattern of cerebral blood flow in mild cognitive …

There is growing recognition that cerebral hypoperfusion is related to the pathogenesis of
Alzheimer's disease (AD), implicating the measurement of cerebral blood flow (CBF) as a …

Atrophy of the medial temporal lobe, especially the hippocampus and the parahippocampal
gyrus, is considered to be the most predictive structural brain biomarker for Alzheimer's …

We compared the predictive value of cerebral perfusion as measured by arterial-spin
labeling magnetic resonance imaging (ASL-MRI) with MRI-derived hippocampal volume for …

The construct of mild cognitive impairment (MCI) has been proposed to identify patients at
risk of developing Alzheimer's disease (AD) in the pre-clinical stage. Although subjects with …

Objective To assess the contribution of regional grey matter (GM) atrophy and functional
disconnection in determining the level of cognitive decline in patients with Alzheimer's …

Machine learning methods have successfully been used to predict the conversion of mild
cognitive impairment (MCI) to Alzheimer's disease (AD), by classifying MCI converters (MCI …