Candida auris: Epidemiology, biology, antifungal resistance, and virulence

H Du, J Bing, T Hu, CL Ennis, CJ Nobile… - PLoS …, 2020 - journals.plos.org
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida
auris is becoming a worldwide public health threat that has been attracting considerable …

Candida auris—the growing menace to global health

SA Lone, A Ahmad - Mycoses, 2019 - Wiley Online Library
summary A paradigm shift of candidiasis from Candida albicans to non‐albicans Candida
species has fundamentally increased with the advent of C. auris. C. auris, despite being a …

Exploring the bioactive sites of new sulfonamide metal chelates for multi-drug resistance: an experimental versus theoretical design

AU Hassan, SH Sumrra - … of Inorganic and Organometallic Polymers and …, 2022 - Springer
During this report, the synthesis, characterization, medicinal, and molecular modeling of
newly synthesized, bidentate sulfonamide metal (VO 2+, Co 2+, Ni 2+, Cu 2+, and Zn 2+) …

What Do We Know about Candida auris? State of the Art, Knowledge Gaps, and Future Directions

V Garcia-Bustos, MD Cabanero-Navalon, A Ruiz-Saurí… - Microorganisms, 2021 - mdpi.com
Candida auris has unprecedently emerged as a multidrug resistant fungal pathogen,
considered a serious global threat due to its potential to cause nosocomial outbreaks and …

Combined antifungal resistance and biofilm tolerance: the global threat of Candida auris

R Kean, G Ramage - Msphere, 2019 - Am Soc Microbiol
The enigmatic yeast Candida auris has emerged over the last decade and rapidly
penetrated our consciousness. The global threat from this multidrug-resistant yeast has …

Candida auris: A Quick Review on Identification, Current Treatments, and Challenges

L Černáková, M Roudbary, S Brás, S Tafaj… - International journal of …, 2021 - mdpi.com
Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in
the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has …

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

KR Iyer, K Camara, M Daniel-Ivad, R Trilles… - Nature …, 2020 - nature.com
Candida auris is an emerging fungal pathogen that exhibits resistance to multiple drugs,
including the most commonly prescribed antifungal, fluconazole. Here, we use a …

Emerging and future strategies in the management of recalcitrant Candida auris

N Bandara, L Samaranayake - Medical Mycology, 2022 - academic.oup.com
Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …

Augmenting azoles with drug synergy to expand the antifungal toolbox

A Kane, DA Carter - Pharmaceuticals, 2022 - mdpi.com
Fungal infections impact the lives of at least 12 million people every year, killing over 1.5
million. Wide-spread use of fungicides and prophylactic antifungal therapy have driven …

Review on plant-based management in combating antimicrobial resistance-mechanistic perspective

M Arip, M Selvaraja, LF Tan, MY Leong… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial resistance (AMR) occurs when microbes no longer respond to any
pharmacological agents, rendering the conventional antimicrobial agents ineffective. AMR …