Leishmania is a genus of protozoan parasites that are transmitted by the bite of
phlebotomine sandflies and give rise to a range of diseases (collectively known as …

Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …

Immune-modulating therapies have revolutionized the treatment of chronic diseases,
particularly cancer. However, their success is restricted and there is a need to identify new …

Unicellular eukaryotes of the genus Leishmania are collectively responsible for a
heterogeneous group of diseases known as leishmaniasis. The visceral form of …

Although several reviews on canine leishmaniasis have been published, none thoroughly
described clinicopathologic abnormalities and their clinical usefulness. The aim of this …

Leishmania are protozoan parasites that predominantly reside in myeloid cells within their
mammalian hosts. Monocytes and macrophages play a central role in the pathogenesis of …

Leishmaniasis is a vector-borne neglected tropical disease associated with a spectrum of
clinical manifestations, ranging from self-healing cutaneous lesions to fatal visceral …

Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania
donovani and Leishmania infantum (Leishmania chagasi in the Americas). These …

Leishmania donovani causes visceral leishmaniasis (VL) where the parasite infects and
resides inside liver and spleen tissue macrophages. Given the abnormal lipid profile …

Leishmaniasis remains a major public health problem worldwide and is classified as
Category I by the TDR/WHO, mainly due to the absence of control. Many experimental …