Approved nanomedicine against diseases

Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …

Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

[HTML][HTML] Liposomes and liposome-like nanoparticles: From anti-fungal infection to the COVID-19 pandemic treatment

Y He, W Zhang, Q Xiao, L Fan, D Huang… - Asian Journal of …, 2022 - Elsevier
The liposome is the first nanomedicine transformed into the market and applied to human
patients. Since then, such phospholipid bilayer vesicles have undergone technological …

Advanced drug-delivery approaches in managing P53-mediated lung diseases remodeling

AA Bhat, R Gilhotra, Y Singh, S Sharma… - …, 2023 - Taylor & Francis
Due to stimulation by invading endogenous signals or pathogens such as injured cells,
inflammation may result in tissue healing or, if left uncontrolled, may cause disease …

Biomimetic nanoparticle-mediated target delivery of hypoxia-responsive plasmid of angiotensin-converting enzyme 2 to reverse hypoxic pulmonary hypertension

R Yuan, M Liu, Y Cheng, F Yan, X Zhu, S Zhou… - ACS …, 2023 - ACS Publications
Hypoxic pulmonary hypertension (HPH) is characterized by pulmonary vascular sustained
constriction and progressive remodeling, which are initiated by hypoxia then with hypoxia …

Cell membrane-coated mesoporous silica nanorods overcome sequential drug delivery barriers against colorectal cancer

J Wang, H Pan, J Li, D Nie, Y Zhuo, Y Lv, N Wang… - Chinese Chemical …, 2023 - Elsevier
Local delivery of nanomedicines holds therapeutic promise for colorectal cancer (CRC).
However, it presents tremendous challenges due to the existence of multiple physiological …

Carrier-free nanodrugs: from bench to bedside

F Fang, X Chen - ACS nano, 2024 - ACS Publications
Carrier-free nanodrugs with extraordinary active pharmaceutical ingredient (API) loading
(even 100%), avoidable carrier-induced toxicity, and simple synthetic procedures are …

COVID-19 inflammation and implications in drug delivery

M Zoulikha, F Huang, Z Wu, W He - Journal of Controlled Release, 2022 - Elsevier
Growing evidence indicates that hyperinflammatory syndrome and cytokine storm observed
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …

[HTML][HTML] Mechanistic and therapeutic perspectives of baicalin and baicalein on pulmonary hypertension: A comprehensive review

L Cui, T Yuan, Z Zeng, D Liu, C Liu, J Guo… - Biomedicine & …, 2022 - Elsevier
Pulmonary hypertension (PH) is a chronic and fatal disease, for which new therapeutic
drugs and approaches are needed urgently. Baicalein and baicalin, the active compounds …

Nanomedicine-mediated therapeutic approaches for pulmonary arterial hypertension

E Mirhadi, P Kesharwani, TP Johnston… - Drug Discovery Today, 2023 - Elsevier
Highlights•Nanomedicine has emerged as a field with great opportunities to improve
treatment strategies.•Pulmonary arterial hypertension (PAH) is a serious and incurable …