Members of the genus Brucella are pathogenic bacteria exceedingly well adapted to their
hosts. The bacterium is transmitted by direct contact within the same host species or …

Remarkable genetic diversity and breadth of host species has been uncovered in the
Brucella genus over the past decade, fundamentally changing our concept of what it means …

Brucella is a facultative intracellular pathogen that causes zoonotic infection known as
brucellosis which results in abortion and infertility in natural host. Humans, especially in low …

High-throughput DNA sequencing enables large-scale metagenomic analyses of complex
biological systems. Such analyses are not restricted to present-day samples and can also be …

Simple Summary There is a wide variety of diseases caused by bacteria, viruses, and
parasites that are transmitted to humans by different routes from other animals. These …

This perspective draws on the record of ancient pathogen genomes and microbiomes
illuminating patterns of infectious disease over the course of the Holocene in order to …

ABSTRACT High quality Altai Neanderthal and Denisovan genomes are revealing which
regions of archaic hominin DNA have persisted in the modern human genome. A number of …

Groundbreaking studies conducted in the mid-1980s demonstrated the possibility of
sequencing ancient DNA (aDNA), which has allowed us to answer fundamental questions …

Zoonotic pathogens are frequently hypothesized as emerging with the origins of farming, but
evidence of this is elusive in the archaeological records. To explore the potential impact of …

Shotgun metagenomics provides a powerful assumption-free approach to the recovery of
pathogen genomes from contemporary and historical material. We sequenced the …