Challenges of neuropathic pain: focus on diabetic neuropathy

DC Rosenberger, V Blechschmidt… - Journal of Neural …, 2020 - Springer
Neuropathic pain is a frequent condition caused by a lesion or disease of the central or
peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain …

The role of advanced glycation end-products in the development of coronary artery disease in patients with and without diabetes mellitus: a review

SL Fishman, H Sonmez, C Basman, V Singh… - Molecular …, 2018 - Springer
Background Traditional risk factors are insufficient to explain all cases of coronary artery
disease (CAD) in patients with diabetes mellitus (DM). Advanced glycation end-products …

Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Understanding diabetic neuropathy: focus on oxidative stress

L Pang, X Lian, H Liu, Y Zhang, Q Li… - Oxidative Medicine …, 2020 - Wiley Online Library
Diabetic neuropathy is one of the clinical syndromes characterized by pain and substantial
morbidity primarily due to a lesion of the somatosensory nervous system. The burden of …

Role of advanced glycation end products in diabetic neuropathy

K Sugimoto, M Yasujima… - Current pharmaceutical …, 2008 - ingentaconnect.com
Diabetic neuropathy is the commonest form of peripheral neuropathy in the developed
countries of the world. In diabetic patients, the presence of peripheral neuropathy increases …

[HTML][HTML] Diabetic painful and insensate neuropathy: pathogenesis and potential treatments

IG Obrosova - Neurotherapeutics, 2009 - Elsevier
Advanced peripheral diabetic neuropathy (PDN) is associated with elevated vibration and
thermal perception thresholds that progress to sensory loss and degeneration of all fiber …

Peripheral neuropathy: pathogenic mechanisms and alternative therapies.

KA Head - Alternative medicine review, 2006 - search.ebscohost.com
Peripheral neuropathy (PN), associated with diabetes, neurotoxic chemotherapy, human
immunodeficiency virus (HIV)/antiretroviral drugs, alcoholism, nutrient deficiencies, heavy …

Diabetic neuropathy: A narrative review of risk factors, classification, screening and current pathogenic treatment options

A Bondar, AR Popa, N Papanas… - Experimental and …, 2021 - spandidos-publications.com
Diabetic neuropathy (DN) is a frequent complication of diabetes mellitus (DM) with severe
consequences as it progresses and influences all human body systems. This review …

Thiamine deficiency in diabetes mellitus and the impact of thiamine replacement on glucose metabolism and vascular disease

GLJ Page, D Laight… - International journal of …, 2011 - Wiley Online Library
Despite the targeting of traditional risk factors for cardiovascular disease, disease burden
has not been completely eliminated. Thiamine is an essential cofactor in carbohydrate …

Neuroprotective effects of thiamine and precursors with higher bioavailability: focus on benfotiamine and dibenzoylthiamine

M Sambon, P Wins, L Bettendorff - International journal of molecular …, 2021 - mdpi.com
Thiamine (vitamin B1) is essential for brain function because of the coenzyme role of
thiamine diphosphate (ThDP) in glucose and energy metabolism. In order to compensate …