Cellular biology of fracture healing

CS Bahney, RL Zondervan, P Allison… - Journal of …, 2019 - Wiley Online Library
The biology of bone healing is a rapidly developing science. Advances in transgenic and
genetargeted mice have enabled tissue and cellspecific investigations of skeletal …

Bringing new life to damaged bone: the importance of angiogenesis in bone repair and regeneration

S Stegen, N Van Gastel, G Carmeliet - Bone, 2015 - Elsevier
Bone has the unique capacity to heal without the formation of a fibrous scar, likely because
several of the cellular and molecular processes governing bone healing recapitulate the …

Vascularized 3D printed scaffolds for promoting bone regeneration

Y Yan, H Chen, H Zhang, C Guo, K Yang, K Chen… - Biomaterials, 2019 - Elsevier
Abstract 3D printed scaffolds hold promising perspective for bone tissue regeneration.
Inspired by process of bone development stage, 3D printed scaffolds with rapid internal …

A novel self-healing polydopamine-functionalized chitosan-arginine hydrogel with enhanced angiogenic and antibacterial activities for accelerating skin wound …

Z Ling, Z Chen, J Deng, Y Wang, B Yuan… - Chemical Engineering …, 2021 - Elsevier
Skin wound healing occurs via a series of orchestrated cellular and molecular events in a
highly ordered manner, in which insufficient angiogenesis and infection at the wound site …

3D printing of a lithium-calcium-silicate crystal bioscaffold with dual bioactivities for osteochondral interface reconstruction

L Chen, C Deng, J Li, Q Yao, J Chang, L Wang, C Wu - Biomaterials, 2019 - Elsevier
It is difficult to achieve self-healing outcoming for the osteochondral defects caused by
degenerative diseases. The simultaneous regeneration of both cartilage and subchondral …

[HTML][HTML] Lotus seedpod-inspired internal vascularized 3D printed scaffold for bone tissue repair

X Han, M Sun, B Chen, Q Saiding, J Zhang, H Song… - Bioactive materials, 2021 - Elsevier
In the field of bone defect repair, 3D printed scaffolds have the characteristics of
personalized customization and accurate internal structure. However, how to construct a …

Angiogenesis in bone regeneration

KD Hankenson, M Dishowitz, C Gray, M Schenker - Injury, 2011 - Elsevier
Angiogenesis is a key component of bone repair. New blood vessels bring oxygen and
nutrients to the highly metabolically active regenerating callus and serve as a route for …

HIF1α ameliorates tubular injury in diabetic nephropathy via HO1–mediated control of mitochondrial dynamics

N Jiang, H Zhao, Y Han, L Li, S Xiong, L Zeng… - Cell …, 2020 - Wiley Online Library
Objectives In diabetic nephropathy (DN), hypoxiainducible factor1α (HIF1α) activation in
tubular cells plays an important protective role against kidney injury. The effects may occur …

[HTML][HTML] The haematoma and its role in bone healing

H Schell, GN Duda, A Peters, S Tsitsilonis… - Journal of experimental …, 2017 - Springer
Fracture treatment is an old endeavour intended to promote bone healing and to also
enable early loading and regain of function in the injured limb. However, in today's clinical …

Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration

DHR Kempen, L Lu, A Heijink, TE Hefferan… - Biomaterials, 2009 - Elsevier
Bone regeneration is a coordinated cascade of events regulated by several cytokines and
growth factors. Angiogenic growth factors are predominantly expressed during the early …