Methotrexate (MTX) is the first line drug for the treatment of a number of rheumatic and non-
rheumatic disorders. It is currently used as an anchor disease, modifying anti-rheumatic drug …

Rheumatoid arthritis (RA) is a heterogeneous autoimmune inflammatory disorder defined by
the damage to the bone and cartilage in the synovium, which causes joint impairment and …

Currently, carriers of active ingredients in the form of particles of a size measured in
nanometers are the focus of interest of research centers worldwide. So far, submicrometer …

Nano-emulgel is an emerging drug delivery system intended to enhance the therapeutic
profile of lipophilic drugs. Lipophilic formulations have a variety of limitations, which includes …

Research and development in health care industry is in persistence progression. To make it
more patient-friendly or to get maximum benefits from it, special attention to different …

At present, several drug molecules have been used for the treatment of rheumatoid arthritis
(RA). However, the utilization of these compounds through the oral and parenteral route is …

Chitosan (Ch)-coated nanostructured lipid carriers (NLCs) have great potential for
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease associated with
persistent multiarticular synovitis, cartilage destruction, and even loss of joint function …

Highlights•The most representative nanomaterials for bone drug delivery are summarized.•
Nanomaterials can target bone by oral, implant, injectable, and transdermal …

Rheumatoid arthritis (RA), a chronic and joint-related autoimmune disease, results in
immune dysfunction and destruction of joints and cartilages. Small molecules and biological …