Medication-induced nephrotoxicity remains one of the most common causes of acute kidney
injury (AKI) among hospitalized patients. Within the extensive group of medications …

Drug-induced kidney injury is a major side effect in clinical practice, frequently leading to
acute renal failure (ARF). It accounts for more than 2% to 15% of cases of ARF in patients …

Several medications—notably acyclovir, sulfonamides, methotrexate, indinavir, and
triamterene—are associated with the production of crystals that are insoluble in human …

Therapeutic agents induce acute renal failure (ARF) by promoting various types of injury to
the kidney. Acute interstitial nephritis (AIN) develops from medications that incite an allergic …

Medications cause renal failure through a variety of mechanisms. Hemodynamic renal
failure may result from drugs that reduce renal prostaglandins and hence renal blood flow …

Medications cause renal disease by promoting various types of injury in the kidney. Several
drugs reduce renal perfusion and cause prerenal azotemia. Vascular disease can develop …

Objectives: 1) To determine the incidence and severity of hyperkalemia during trimethoprim
therapy. 2) To test the hypothesis that trimethoprim inhibits renal potassium excretion by …

Highly active antiretroviral therapy (HAART) and other medical therapies for HIV‐related
infections have been associated with toxicities. Antiretroviral therapy can contribute to renal …

Background: Several medications that are insoluble in human urine are known to precipitate
within the renal tubules. Intratubular precipitation of either exogenously administered …

Objective: To determine the effect of standard-dose trimethoprim-sulfamethoxazole on
serum potassium concentration in hospitalized patients. Design: Prospective chart review …