Neurodegenerative diseases (ND) primarily affect the neurons in the human brain
secondary to oxidative stress and neuroinflammation. ND are more common and have a …

Neuropsychiatric disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD)
and depression, have seriously inconvenienced the lives of patients. Growing evidence …

OBJECTIVES: Many species of the Caatinga flora are used as medicines in local
communities. In recent decades, the knowledge and use of these species has been …

α-Synuclein (αS) assembly has been implicated as a critical step in the development of
Lewy body diseases such as Parkinson's disease and dementia with Lewy bodies …

Preventing the abnormal assembly of α-synuclein (α-Syn) and the correct modulation of
vitagenes system exercise strong neuroprotective effects. It has been reported that …

Chalcones belong to a class of biologically active polyphenolic natural products. As a result
of their simple chemical nature, they are easily synthesized and show a variety of promising …

The validity of the chalcone scaffold for the design of inhibitors of monoamine oxidase has
previously been illustrated. In a systematic attempt to investigate the effect of heterocyclic …

Nas pesquisas com fitoterápicos o uso popular pode sugerir espécies potencialmente
importantes, porém, faz-se necessário uma série de estudos, entre eles, a identificação de …

Abstract Ethnopharmacological relevance Myracrodruon urundeuva Allemão (Aroeira-do-
Sertão), Anacardiaceae, is one of the most used plants in folk medicine in Northeastern …

This study was designed to evaluate the neuroprotective activity of ethanol extract of
Pongamia pinnata stem bark in monosodium glutamate-induced neurotoxicity in rats …