Computed tomography in acute intracerebral hemorrhage: neuroimaging predictors of hematoma expansion and outcome

A Hillal, T Ullberg, B Ramgren, J Wassélius - Insights into imaging, 2022 - Springer
Intracerebral hemorrhage (ICH) accounts for 10–20% of all strokes worldwide and is
associated with serious outcomes, including a 30-day mortality rate of up to 40 …

Molecular, pathological, clinical, and therapeutic aspects of perihematomal edema in different stages of intracerebral hemorrhage

C Jiang, H Guo, Z Zhang, Y Wang, S Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Acute intracerebral hemorrhage (ICH) is a devastating type of stroke worldwide. Neuronal
destruction involved in the brain damage process caused by ICH includes a primary injury …

Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage

S Pszczolkowski, JP Manzano-Patrón, ZK Law… - European …, 2021 - Springer
Objectives To test radiomics-based features extracted from noncontrast CT of patients with
spontaneous intracerebral haemorrhage for prediction of haematoma expansion and poor …

The association between perihaematomal oedema and functional outcome after spontaneous intracerebral haemorrhage: A systematic review and meta-analysis

MP Cliteur, L Sondag, L Cunningham… - European Stroke …, 2023 - journals.sagepub.com
Purpose: Perihaematomal oedema (PHO) formation has gained increasing interest as a
therapeutic target after spontaneous intracerebral haemorrhage (ICH). Whether PHO …

Phase II randomised, placebo-controlled, clinical trial of interleukin-1 receptor antagonist in intracerebral haemorrhage: BLOcking the Cytokine IL-1 in ICH (BLOC-ICH …

AR Parry-Jones, K Stocking… - European Stroke …, 2023 - journals.sagepub.com
Purpose: Recombinant human interleukin-1 receptor antagonist (anakinra) is an anti-
inflammatory with efficacy in animal models of stroke. We tested the effect of anakinra on …

Perihematomal edema and clinical outcome after intracerebral hemorrhage: a systematic review and meta-analysis

S Marchina, JA Trevino-Calderon, S Hassani… - Neurocritical care, 2022 - Springer
Background Perihematomal edema (PHE) has been proposed as a radiological marker of
secondary injury and therapeutic target in intracerebral hemorrhage (ICH). We conducted a …

[HTML][HTML] Perihematomal edema-based CT-radiomics model to predict functional outcome in patients with intracerebral hemorrhage

X Huang, D Wang, Y Ma, Q Zhang, J Ren… - Diagnostic and …, 2023 - Elsevier
Purpose The purpose of this study was to identify possible association between noncontrast
computed tomography (NCCT)-based radiomics features of perihematomal edema (PHE) …

The Hounsfield unit of perihematomal edema is associated with poor clinical outcomes in intracerebral hemorrhage

R Huan, Y Li, J Tan, J Tang, N Huang, Y Cheng - World Neurosurgery, 2021 - Elsevier
Background Hounsfield unit (HU) of perihematomal edema (PHE) may be a predictor of
prognosis of intracerebral hemorrhage (ICH). Our study evaluated whether PHE mean HU at …

An updated systematic review and meta-analysis investigating perihematomal edema and clinical outcome after intracerebral hemorrhage

S Marchina, KH Lee, VA Lioutas, F Carvalho… - Journal of Stroke and …, 2023 - Elsevier
Objectives The relationship between perihematomal edema (PHE) and intracerebral
hemorrhage (ICH) outcomes is uncertain. Given newly published studies, we updated a …

Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: a community …

JJM Loan, AB Gane, L Middleton… - … journal of stroke, 2021 - journals.sagepub.com
Background Hospital-based studies have reported variable associations between outcome
after spontaneous intracerebral hemorrhage and peri-hematomal edema volume. Aims In a …