Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional
groups to explore and understand biology in living organisms. In this review, we summarize …

Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

Bioorthogonal chemistries enable researchers to interrogate biomolecules in living systems.
These reactions are highly selective and biocompatible, and can be performed in many …

In the past 15 years, there have been rapid developments in the ability to cotranslationally
incorporate unnatural amino acids into proteins produced in cells, both at defined sites via …

The research on 1, 2, 3-triazoles has been lively and ever-growing since its stimulation by
the advent of click chemistry. The attractiveness of 1H-1, 2, 3-triazoles and their derivatives …

Despite originating only a little more than a decade ago, click chemistry has become one of
the most powerful paradigms in materials science, synthesis, and modification. By …

Much of life's complexity depends upon contacts between proteins with precise affinity and
specificity. The successful application of engineered proteins often depends on high-stability …

Over the past 15 years a great deal of progress has been made on the discovery,
rediscovery, and invention of bioorthogonal reactions between functional groups that do not …

The inner mitochondrial membrane (IMM) generates power to drive cell function, and its
dynamics control mitochondrial health and cellular homeostasis. Here, we describe the cell …