The 5-membered oxadiazole and thiadiazole scaffolds are the most privileged and well-
known heterocycles, being a common and essential feature of a variety of natural products …

Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

With the increasing number of cases of inactive and drug-resistance tuberculosis, there is an
urgent need to develop new potent molecules set for fighting this brutal disease. Medicinal …

The therapeutic potential of the benzimidazole nucleus has been recognized since 1944,
and it is an important heterocycle system due to its presence in a wide range of bioactive …

The first one-pot room-temperature protocol for the synthesis of 3, 5-disubstituted-1, 2, 4-
oxadiazoles via the condensation between amidoximes and carboxylic acid esters in …

Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

Improving lipophilicity for drugs to penetrate the lipid membrane and decreasing bacterial
and fungal coinfections for patients with cancer pose challenges in the drug development …

With the increasing number of cases of latent and drug resistant tuberculosis, there is an
urgent need to develop new, potent molecules capable of combating this deadly disease …

An intramolecular sp3 C–H amination reaction of aniline derivatives has been established.
This reaction employs molecular iodine (I2) under transition-metal-free conditions and …

An electrochemical dehydrogenative amination for the synthesis of benzimidazoles was
developed. This electrosynthesis method could address the limitations of the C (sp3)–H …