The first report of trans-acting RNA-based regulation in bacterial cells dates back to 1984.
Subsequent studies in diverse bacteria unraveled shared properties of trans-acting small …

Clostridium organisms are of major importance in the development of technologies to
produce biofuels and chemicals. They are uniquely capable of utilizing virtually all biomass …

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen responsible for
significant human morbidity and mortality. Post-transcriptional regulation by small RNAs …

RNA-sequencing has led to a spectacular increase in the repertoire of bacterial sRNAs and
improved our understanding of their biological functions. Bacterial sRNAs have also been …

Data-driven machine learning is the method of choice for predicting molecular phenotypes
from nucleotide sequence, modeling gene expression events including protein-DNA …

In eukaryotic organisms, transfer RNA (tRNA)-derived fragments have diverse biological
functions. Considering the conserved sequences of tRNAs, it is not surprising that …

Background Low-temperature expression of recombinant proteins may be advantageous to
support their proper folding and preserve bioactivity. The generation of expression vectors …

Streptomyces lividans is an attractive host for production of heterologous proteins and
secondary metabolites of other Streptomyces species. To fully harness the industrial …

Enteroaggregative Escherichia coli (EAEC) strains are one of the diarrheagenic pathotypes.
EAEC strains harbor a virulence plasmid (pAA2) that encodes, among other virulence …

Bordetella pertussis is the causative agent of whooping cough, a respiratory disease still
considered as a major public health threat and for which recent re-emergence has been …