Traumatic brain injury and risk of neurodegenerative disorder

BL Brett, RC Gardner, J Godbout, K Dams-O'Connor… - Biological …, 2022 - Elsevier
Traumatic brain injury (TBI), particularly of greater severity (ie, moderate to severe), has
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …

Epidemiology of mild traumatic brain injury and neurodegenerative disease

RC Gardner, K Yaffe - Molecular and Cellular Neuroscience, 2015 - Elsevier
Every year an estimated 42 million people worldwide suffer a mild traumatic brain injury
(MTBI) or concussion. More severe traumatic brain injury (TBI) is a well-established risk …

The neuropathology and cerebrovascular mechanisms of dementia

L Raz, J Knoefel, K Bhaskar - Journal of Cerebral Blood Flow …, 2016 - journals.sagepub.com
The prevalence of dementia is increasing in our aging population at an alarming rate.
Because of the heterogeneity of clinical presentation and complexity of disease …

Traumatic brain injury and risk of dementia in older veterans

DE Barnes, A Kaup, KA Kirby, AL Byers… - Neurology, 2014 - AAN Enterprises
Objectives: Traumatic brain injury (TBI) is common in military personnel, and there is
growing concern about the long-term effects of TBI on the brain; however, few studies have …

Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine

DJ Irwin, NJ Cairns, M Grossman, CT McMillan… - Acta …, 2015 - Springer
Frontotemporal lobar degeneration (FTLD) comprises two main classes of
neurodegenerative diseases characterized by neuronal/glial proteinaceous inclusions (ie …

Polypathology and dementia after brain trauma: Does brain injury trigger distinct neurodegenerative diseases, or should they be classified together as traumatic …

PM Washington, S Villapol, MP Burns - Experimental neurology, 2016 - Elsevier
Neuropathological studies of human traumatic brain injury (TBI) cases have described
amyloid plaques acutely after a single severe TBI, and tau pathology after repeat mild TBI …

What is the relationship of traumatic brain injury to dementia?

MF Mendez - Journal of Alzheimer's disease, 2017 - content.iospress.com
There is a long history linking traumatic brain injury (TBI) with the development of dementia.
Despite significant reservations, such as recall bias or concluding causality for TBI, a …

Frontotemporal dementias

EC Finger - Continuum: Lifelong Learning in Neurology, 2016 - journals.lww.com
Abstract Purpose of Review: This article reviews the common behavioral and cognitive
features of frontotemporal dementia (FTD) and related disorders as well as the …

Dementia in military and veteran populations: a review of risk factors—traumatic brain injury, post-traumatic stress disorder, deployment, and sleep

Z Raza, SF Hussain, S Ftouni, G Spitz, N Caplin… - Military medical …, 2021 - Springer
The military population face a unique set of risk factors that may increase the risk of being
diagnosed with dementia. Traumatic brain injury (TBI) and post-traumatic stress disorder …

Traumatic brain injury and risk of long-term brain changes, accumulation of pathological markers, and developing dementia: a review

C LoBue, C Munro, J Schaffert… - Journal of …, 2019 - content.iospress.com
Traumatic brain injuries (TBI) have received widespread media attention in recent years as
being a risk factor for the development of dementia and chronic traumatic encephalopathy …