[HTML][HTML] Effect of paraquat on cytotoxicity involved in oxidative stress and inflammatory reaction: A review of mechanisms and ecological implications
J Chen, Y Su, F Lin, M Iqbal, K Mehmood… - Ecotoxicology and …, 2021 - Elsevier
Paraquat (PQ) is a cheap and an effective herbicide, which is widely being used worldwide
to remove weeds in cultivated crop fields. However, it can cause soil and water pollution …
to remove weeds in cultivated crop fields. However, it can cause soil and water pollution …
Behavioral tests in neurotoxin-induced animal models of Parkinson's disease
Currently, neurodegenerative diseases are a major cause of disability around the world.
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …
An alternative explanation for Alzheimer's disease and Parkinson's disease initiation from specific antibiotics, gut microbiota dysbiosis and neurotoxins
K Roe - Neurochemical Research, 2022 - Springer
The late onset neuropathologies, including Alzheimer's disease and Parkinson's disease,
have become increasingly prevalent. Their causation has been linked to genetics, gut …
have become increasingly prevalent. Their causation has been linked to genetics, gut …
[HTML][HTML] Mood disturbances in Parkinson's disease: From prodromal origins to application of animal models
Parkinson's disease (PD) is a complex illness with a constellation of environmental insults
and genetic vulnerabilities being implicated. Strikingly, many studies only focus on the …
and genetic vulnerabilities being implicated. Strikingly, many studies only focus on the …
The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson's disease
Z Dwyer, M Chaiquin, J Landrigan, K Ayoub… - Journal of …, 2021 - Springer
Background Recent work has established that Parkinson's disease (PD) patients have an
altered gut microbiome, along with signs of intestinal inflammation. This could help explain …
altered gut microbiome, along with signs of intestinal inflammation. This could help explain …
Characterizing the protracted neurobiological and neuroanatomical effects of paraquat in a murine model of Parkinson's disease
The primary motor symptoms of Parkinson's disease (PD) result from the degeneration of
dopamine-producing neurons of the substantia nigra pars compacta (SNc), and often, the …
dopamine-producing neurons of the substantia nigra pars compacta (SNc), and often, the …
Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype
Background Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in
Parkinson's disease (PD) and is also thought to be fundamentally involved in numerous …
Parkinson's disease (PD) and is also thought to be fundamentally involved in numerous …
[HTML][HTML] Chronic unpredictable stress influenced the behavioral but not the neurodegenerative impact of paraquat
The impact of psychological stressors on the progression of motor and non-motor
disturbances observed in Parkinson's disease (PD) has received little attention. Given that …
disturbances observed in Parkinson's disease (PD) has received little attention. Given that …
Paraquat increases Interleukin-1β in hippocampal dentate gyrus to impair hippocampal neurogenesis in adult mice
Q Li, H Xiao, Y Shao, X Chang, Y Zhang… - … and Environmental Safety, 2020 - Elsevier
Abstract Paraquat (1, 1′-dimethyl-4, 4′-bipyridium dichloride, PQ), a non-selective and
efficient herbicide, causes neuroinflammation, neurodegeneration and memory dysfunction …
efficient herbicide, causes neuroinflammation, neurodegeneration and memory dysfunction …
Early life selective knockdown of the TrkB receptor and maternal separation modulates adult stress phenotype
N Prowse, Z Dwyer, A Thompson, T Fortin… - Behavioural Brain …, 2020 - Elsevier
Abstract Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that has been
implicated in mood and anxiety disorders and is upregulated by antidepressants. It has …
implicated in mood and anxiety disorders and is upregulated by antidepressants. It has …