Primary biliary cholangitis: Epidemiology, prognosis, and treatment

J Trivella, BV John, C Levy - Hepatology communications, 2023 - journals.lww.com
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease
characterized by a destructive, small duct, and lymphocytic cholangitis, and marked by the …

[HTML][HTML] Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis

S Sarcognato, D Sacchi, F Grillo, N Cazzagon… - Pathologica, 2021 - ncbi.nlm.nih.gov
Autoimmune cholestatic liver diseases are rare hepato-biliary disorders characterized by a
progressive, inflammatory destruction of bile ducts. Primary biliary cholangitis (PBC) and …

A phase 3 trial of seladelpar in primary biliary cholangitis

GM Hirschfield, CL Bowlus, MJ Mayo… - … England Journal of …, 2024 - Mass Medical Soc
Background Effective treatments for patients with primary biliary cholangitis are limited.
Seladelpar, a peroxisome proliferator–activated receptor delta agonist, has potential …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

CPG Panel, A Berzigotti, E Tsochatzis, J Boursier… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

[PDF][PDF] Primary biliary cholangitis: 2018 practice guidance from the American Association for the Study of Liver Diseases

KD Lindor, CL Bowlus, J Boyer, C Levy, M Mayo - Hepatology, 2019 - Wiley Online Library
This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance
on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009 …

[HTML][HTML] A placebo-controlled trial of bezafibrate in primary biliary cholangitis

C Corpechot, O Chazouillères… - … England Journal of …, 2018 - Mass Medical Soc
Background Patients with primary biliary cholangitis who have an inadequate response to
therapy with ursodeoxycholic acid are at high risk for disease progression. Fibrates, which …

EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis

GM Hirschfield, U Beuers, C Corpechot, P Invernizzi… - Journal of …, 2017 - Elsevier
Primary biliary cholangitis (PBC) is a chronic inflammatory autoimmune cholestatic liver
disease, which when untreated will culminate in end-stage biliary cirrhosis. Diagnosis is …

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

GM Hirschfield, JK Dyson, GJM Alexander… - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …

[HTML][HTML] A randomized placebo-controlled trial of elafibranor in patients with primary biliary cholangitis and incomplete response to UDCA

JM Schattenberg, A Pares, KV Kowdley… - Journal of …, 2021 - Elsevier
Background & Aims Patients with primary biliary cholangitis (PBC) who have an incomplete
response to ursodeoxycholic acid remain at risk of disease progression. We investigated the …

APASL clinical practice guidance: the diagnosis and management of patients with primary biliary cholangitis

H You, X Ma, C Efe, G Wang, SH Jeong, K Abe… - Hepatology …, 2022 - Springer
Hong You1· Xiong Ma2· Cumali Efe3· Guiqiang Wang4· Sook‑Hyang Jeong5· Kazumichi
Abe6· Weijia Duan1· Sha Chen1· Yuanyuan Kong7· Dong Zhang8· Lai Wei9· Fu‑Sheng …