The genus Pseudomonas described in 1894 is one of the most diverse and ubiquitous
bacterial genera which encompass species isolated worldwide. In the last years more than …

Bacterial biofilms are the basis of many persistent diseases. The persistence of these
infections is primarily attributed to the increased antibiotic resistance exhibited by the cells …

Abstract The Pseudomonas Genome Database (http://www. pseudomonas. com) is well
known for the application of community-based annotation approaches for producing a high …

Recent technological advances have opened unprecedented opportunities for large-scale
sequencing and analysis of populations of pathogenic species in disease outbreaks, as well …

Microbial genome sequencing projects produce numerous sequences of deduced proteins,
only a small fraction of which have been or will ever be studied experimentally. This leaves …

Allelic exchange is an efficient method of bacterial genome engineering. This protocol
describes the use of this technique to make gene knockouts and knock-ins, as well as single …

Abstract The Gene Ontology Annotation (GOA) resource (http://www. ebi. ac. uk/GOA)
provides evidence-based Gene Ontology (GO) annotations to proteins in the UniProt …

Little is known about how within-host evolution compares between genotypically different
strains of the same pathogenic species. We sequenced the whole genomes of 474 …

The increasing prevalence of antibiotic-resistant bacteria is a global threat to public health.
Agricultural use of antibiotics is believed to contribute to the spread of antibiotic resistance …

The mission of the Universal Protein Resource (UniProt)(http://www. uniprot. org) is to
provide the scientific community with a comprehensive, high-quality and freely accessible …