Carbonic anhydrases (CAs, EC 4.2. 1.1) catalyse the interconversion between CO2 and
bicarbonate as well as other hydrolytic reactions. Among the six genetic families known to …

Carbonic anhydrase (CA, EC 4.2. 1.1) is a protein that is especially well-suited to serve as a
model in many types of studies in biophysics, bioanalysis, the physical-organic chemistry of …

Alzheimer's disease is the most common neurodegenerative disease, and there are no
mechanism-based therapies. The disease is defined by the presence of abundant …

Protein complexes of the mitochondrial respiratory chain assemble into respiratory
supercomplexes. Here we present the high-resolution electron cryo-microscopy structure of …

Enzymes fold into unique three-dimensional structures, which underlie their remarkable
catalytic properties. The requirement to adopt a stable, folded conformation is likely to …

Zinc is known to be indispensable to growth and development and transmission of the
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …

Carbonic anhydrases catalyze the reversible hydration of CO2 []. Since the discovery of this
zinc (Zn) metalloenzyme in erythrocytes over 65 years ago, carbonic anhydrase has not only …

The fact that natural β-sheet proteins are usually soluble but that fragments or designs of β
structure usually aggregate suggests that natural β proteins must somehow be designed to …

Carbonic anhydrases (CAs) are zinc metalloenzymes that catalyze the interconversion of
CO 2 and HCO 3− and are ubiquitous in nature. Higher plants contain three evolutionarily …

Carbonic anhydrases (CAs, EC 4.2. 1.1) are zinc enzymes acting as efficient catalysts for the
reversible hydration of carbon dioxide to bicarbonate. 16 different α-CA isoforms were …