Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

NETosis is a program for formation of neutrophil extracellular traps (NETs), which consist of
modified chromatin decorated with bactericidal proteins from granules and cytoplasm …

Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet serious adverse
effect of the adenoviral vector vaccines ChAdOx1 nCoV-19 (AstraZeneca) and Ad26. COV2 …

Over the past millennia, life expectancy has drastically increased. While a mere 25 years
during Bronze and Iron ages, life expectancy in many European countries and in Japan is …

Ischemic stroke prompts a strong inflammatory response, which is associated with
exacerbated outcomes. In this study, we investigated mechanistic regulators of neutrophil …

Innate immunity and chronic inflammation are involved in atherosclerosis and
atherothrombosis, leading to target organ damage in essential hypertension (EH). However …

Both neutrophil extracellular traps (NETs) and von Willebrand factor (VWF) are essential for
thrombosis and inflammation. During these processes, a complex series of events, including …

Human neutrophils, the most abundant circulating leukocytes, are fundamental components
of the host response against different pathogens. Until a few years ago, neutrophils received …

Neutrophil extracellular traps (NETs) comprise decondensed chromatin, histones and
neutrophil granular proteins and are involved in the response to infectious as well as non …