Spexin is the most recently discovered member of the galanin/kisspeptin/spexin family of
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …

It is known that a strong association exists between a suboptimal lifestyle (physical inactivity
and sedentary behavior and/or high calorie diet) and increased propensity of developing …

Adropin is a multifunctional secreted protein, which is involved in the metabolic modulation
of the heart-brain-kidney axis in heart failure (HF). The aim of the study was to detect the …

Physical inactivity is a major cause of chronic diseases. It shortens the health span by
lowering the age of the first chronic disease onset, which leads to decreased quality of life …

Spexin (SPX) is a 14 amino acid length peptide hormone which was discovered using
bioinformatic tools. It is extensively expressed in central and peripheral tissues and secreted …

Matrix metalloproteinase-10 (MMP-10) is a zinc-dependent endopeptidase with the ability to
degrade a broad spectrum of extracellular matrices and other protein substrates. The …

Overview: The treatment of chronic renal failure (CRF) with traditional Chinese medicine has
attracted much attention, but its mechanism is not clear. Network pharmacology is an …

Objective (s): Due to its negative side effects, mainly nephrotoxicity, adriamycin (ADR) is
used fairly infrequently. The purpose of this study is to investigate the effects of N-acetyl …

Background Chronic kidney disease (CKD) is defined as the progressive deterioration of
renal parenchyma and decline in renal unit function. In the early stages of CKD (G1+ G2) …

Chronic kidney disease is one of the major global health problems. Chronic renal failure is
stimulated by many cytokines and chemokines. Adropin and spexin (SPX) are peptides …