The reductive amination, the reaction of an aldehyde or a ketone with ammonia or an amine
in the presence of a reducing agent and often a catalyst, is an important amine synthesis …

Reductive aminations constitute an important class of reactions widely applied in research
laboratories and industries for the synthesis of amines as well as pharmaceuticals …

Asymmetric reductive amination (ARA) of a prochiral carbonyl compound with an amine
using a H2/hydrogen surrogate is a concise and operationally simple method for the …

Plants' bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich
dietary supplements are known to exhibit neuroprotective potential. In this study, we isolated …

A commercially available ruthenium (II) PNP-type pincer catalyst (Ru-Macho) promotes the
formation of α-chiral tert-butanesulfinylamines from racemic secondary alcohols and …

Diabetes mellitus is a metabolic disorder and is a global challenge to the current medicinal
chemists and pharmacologists. This research has been designed to isolate and evaluate …

The chiral drug candidates have more effective binding affinities for their specific protein or
receptor site for the onset of pharmacological action. Achieving all carbon stereopure …

The asymmetric aldol reaction is one of the most powerful synthetic tools for carbon–carbon
bond-forming reactions. This method provides a beneficial route to access chiral β-hydroxy …

Critical parameters affecting the stereoselective amination of (hetero) aromatic ketones
using transaminases have been studied, such as temperature, pH, substrate concentration …

Highly polarized organometallic compounds of s‐block elements are added smoothly to
chiral N‐tert‐butanesulfinyl imines in the biodegradable d‐sorbitol/choline chloride eutectic …