Molecular biomarkers for vascular cognitive impairment and dementia
S Hosoki, GK Hansra, T Jayasena, A Poljak… - Nature Reviews …, 2023 - nature.com
As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …
The pathobiology of vascular dementia
C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …
Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies
K Deckers, MPJ van Boxtel… - … journal of geriatric …, 2015 - Wiley Online Library
Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …
Role of inflammatory markers in the diagnosis of vascular contributions to cognitive impairment and dementia: a systematic review and meta-analysis
C Custodero, A Ciavarella, F Panza, D Gnocchi… - Geroscience, 2022 - Springer
Vascular contribution to cognitive impairment and dementia (VCID) is a clinical label
encompassing a wide range of cognitive disorders progressing from mild to major vascular …
encompassing a wide range of cognitive disorders progressing from mild to major vascular …
Inflammatory markers and the risk of dementia and Alzheimer's disease: a meta-analysis
SKL Darweesh, FJ Wolters, MA Ikram, F de Wolf… - Alzheimer's & …, 2018 - Elsevier
Introduction Inflammatory markers are often elevated in patients with dementia, including
Alzheimer's disease (AD). However, it remains unclear whether inflammatory markers are …
Alzheimer's disease (AD). However, it remains unclear whether inflammatory markers are …
A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development
The allostatic load (AL) model represents an interdisciplinary approach to comprehensively
conceptualize and quantify chronic stress in relation to pathologies throughout the life cycle …
conceptualize and quantify chronic stress in relation to pathologies throughout the life cycle …
[HTML][HTML] Vascular cognitive impairment: disease mechanisms and therapeutic implications
DA Levine, KM Langa - Neurotherapeutics, 2011 - Elsevier
The prevalence of vascular cognitive impairment (VCI) is likely to increase as the population
ages and cardiovascular disease survival improves. We provide an overview of the …
ages and cardiovascular disease survival improves. We provide an overview of the …
Benzodiazepine use and risk of dementia: evidence from the Caerphilly Prospective Study (CaPS)
J Gallacher, P Elwood, J Pickering, A Bayer… - J Epidemiol …, 2012 - jech.bmj.com
Background Benzodiazepine use is widespread in older people, although its benefit is
uncertain. Aim To investigate the long-term effect of benzodiazepine use upon dementia …
uncertain. Aim To investigate the long-term effect of benzodiazepine use upon dementia …
Vascular disease and dementias: paradigm shifts to drive research in new directions
Vascular disease was once considered the principal cause of aging-related dementia. More
recently, however, research emphasis has shifted to studies of progressive …
recently, however, research emphasis has shifted to studies of progressive …
Longitudinal inflammation, cognitive decline, and Alzheimer's disease: a mini‐review
BM Bettcher, JH Kramer - Clinical Pharmacology & …, 2014 - Wiley Online Library
The role of inflammation in cognitive decline has generated considerable interest, although
few longitudinal evaluations have been conducted. A review of the literature yields mixed …
few longitudinal evaluations have been conducted. A review of the literature yields mixed …