Thiol-linked alkylation of RNA to assess expression dynamics

VA Herzog, B Reichholf, T Neumann, P Rescheneder… - Nature …, 2017 - nature.com
Gene expression profiling by high-throughput sequencing reveals qualitative and
quantitative changes in RNA species at steady state but obscures the intracellular dynamics …

SLAMseq resolves the kinetics of maternal and zygotic gene expression during early zebrafish embryogenesis

P Bhat, LE Cabrera-Quio, VA Herzog, N Fasching… - Cell Reports, 2023 - cell.com
The maternal-to-zygotic transition (MZT) is a key developmental process in metazoan
embryos that involves the activation of zygotic transcription (ZGA) and degradation of …

Regulation of cytoplasmic RNA stability: Lessons from Drosophila

BP Towler, SF Newbury - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
The process of RNA degradation is a critical level of regulation contributing to the control of
gene expression. In the last two decades a number of studies have shown the specific and …

SLAM-ITseq: sequencing cell type-specific transcriptomes without cell sorting

W Matsushima, VA Herzog, T Neumann… - …, 2018 - journals.biologists.com
Cell type-specific transcriptome analysis is an essential tool for understanding biological
processes in which diverse types of cells are involved. Although cell isolation methods such …

Sequencing cell-type-specific transcriptomes with SLAM-ITseq

W Matsushima, VA Herzog, T Neumann, K Gapp… - Nature protocols, 2019 - nature.com
Abstract Analysis of cell-type-specific transcriptomes is vital for understanding the biology of
tissues and organs in the context of multicellular organisms. In this Protocol Extension, we …

SLAMseq resolves the kinetics of maternal and zygotic gene expression in early zebrafish embryogenesis

P Bhat, LE Cabrera-Quio, VA Herzog, N Fasching… - bioRxiv, 2022 - biorxiv.org
The maternal-to-zygotic transition (MZT) is a key developmental process in metazoan
embryos that involves the activation of zygotic transcription (ZGA) and degradation of …

Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation

M Modic, IR de Los Mozos, S Steinhauser… - bioRxiv, 2021 - biorxiv.org
The embryonic progression from naïve to primed pluripotency is accompanied by the rapid
decay of pluripotency-associated mRNAs and a concomitant radical morphogenetic …

[PDF][PDF] Regulation of Cytoplasmic RNA Stability: Lessons from

BP Towler, F Sarah - Nucleic Acids Res, 2014 - core.ac.uk
The process of RNA degradation is a critical level of regulation contributing to the control of
gene expression. In the last two decades a number of studies have shown the specific and …