Paediatric HIV infection is a growing health challenge worldwide, with an estimated 1500
new infections every day. In developed countries, well established prevention programmes …

Despite the enormous progress made in scaling up antiretroviral therapy (ART) in sub-
Saharan Africa, many challenges remain, not least of which are the identification and …

Although it is a standard practice in high-income countries, determination of the human
immunodeficiency virus (HIV) load is not recommended in developing countries because of …

Objective: To assess the performance of WHO clinical and CD4 cell count criteria for
antiretroviral treatment (ART) failure among HIV-infected adults in a workplace HIV care …

Background World Health Organization (WHO) guidelines for monitoring HIV-infected
individuals taking combination antiretroviral therapy (cART) in resource-limited settings …

For over twenty years, human immunodeficiency virus (HIV) infection and acquired
immunodeficiency syndrome (AIDS) have been significant public health concerns, and the …

Objectives To determine rates and causes of switching from first-to second-line antiretroviral
treatment (ART) regimens in a large treatment-naive cohort (a South African community …

Objectives: To describe the use of second-line protease-inhibitor regimens in Médecins
Sans Frontières HIV programmes, and determine switch rates, clinical outcomes, and factors …

Background: CD4+ T-lymphocyte (CD4) counts are widely used to monitor response to
antiretroviral therapy (ART) in resource-limited settings. However, the utility of such …

Objectives In antiretroviral therapy (ART) scale‐up programmes in sub‐Saharan Africa viral
load monitoring is not recommended. We wanted to study the impact of only using clinical …