Resveratrol and brain mitochondria: a review

FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

[HTML][HTML] Pathophysiological role of neuroinflammation in neurodegenerative diseases and psychiatric disorders

H Hong, BS Kim, HI Im - International neurourology journal, 2016 - ncbi.nlm.nih.gov
Brain diseases and disorders such as Alzheimer disease, Parkinson disease, depression,
schizophrenia, autism, and addiction lead to reduced quality of daily life through abnormal …

Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer's disease

R Balez, N Steiner, M Engel, SS Muñoz, JS Lum… - Scientific reports, 2016 - nature.com
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases, yet
current therapeutic treatments are inadequate due to a complex disease pathogenesis. The …

Resveratrol and Alzheimer's disease: mechanistic insights

T Ahmed, S Javed, S Javed, A Tariq, D Šamec… - Molecular …, 2017 - Springer
Alzheimer's disease (AD) is the leading cause of dementia in the elderly and is
characterized by progressive cognitive and memory deficits. The pathological hallmarks of …

Phenolic compounds characteristic of the mediterranean diet in mitigating microglia-mediated neuroinflammation

R Hornedo-Ortega, AB Cerezo… - Frontiers in Cellular …, 2018 - frontiersin.org
Neuroinflammation is a pathological feature of quite a number of Central Nervous System
diseases such as Alzheimer and Parkinson's disease among others. The hallmark of brain …

The neuroprotective effects of polyphenols, their role in innate immunity and the interplay with the microbiota

G Annunziata, A Sureda, IE Orhan, M Battino… - Neuroscience & …, 2021 - Elsevier
Neurodegenerative disorders, particularly in the elderly population, represent one of the
most pressing social and health-care problems in the world. Besides the well-established …

Signaling mechanisms underlying inhibition of neuroinflammation by resveratrol in neurodegenerative diseases

J Huang, N Huang, S Xu, Y Luo, Y Li, H Jin… - The Journal of nutritional …, 2021 - Elsevier
Abstract Neurodegenerative diseases (NDs), including Alzheimer's disease (AD), and
Parkinson's disease (PD), are characterized by the progressive loss of the structure and …

Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus

J Huang, N Huang, Q Mao, J Shi, Y Qiu - Frontiers in aging …, 2023 - frontiersin.org
There is a close relationship between Alzheimer's disease (AD) and diabetes mellitus (DM),
and the link between the two is often referred to as type 3 diabetes mellitus (T3DM). Many …

Curcumin and resveratrol in the management of cognitive disorders: what is the clinical evidence?

G Mazzanti, S Di Giacomo - Molecules, 2016 - mdpi.com
A growing body of in vitro and in vivo evidences shows a possible role of polyphenols in
counteracting neurodegeneration: curcumin and resveratrol are attractive substances in this …

Xuefu Zhuyu decoction, a traditional Chinese medicine, provides neuroprotection in a rat model of traumatic brain injury via an anti-inflammatory pathway

Z Xing, Z Xia, W Peng, J Li, C Zhang, C Fu, T Tang… - Scientific reports, 2016 - nature.com
Neuroinflammation is central to the pathology of traumatic brain injury (TBI). Xuefu Zhuyu
decoction (XFZY) is an effective traditional Chinese medicine to treat TBI. To elucidate its …