Functional role of circular RNAs in cancer development and progression
Circular RNAs (circRNAs) are a large class of endogenously expressed non-coding RNAs
formed by covalently closed loops through back-splicing. High throughput sequencing …
formed by covalently closed loops through back-splicing. High throughput sequencing …
Circular RNAs: a new frontier for cancer diagnosis and therapy
M Zhang, Y Xin - Journal of hematology & oncology, 2018 - Springer
In recent years, circular RNAs (circRNAs) have attracted considerable attention because
they play a significant role in many fields of cancer biology. Additionally, it has become …
they play a significant role in many fields of cancer biology. Additionally, it has become …
Exosomal miR-628-5p from M1 polarized macrophages hinders m6A modification of circFUT8 to suppress hepatocellular carcinoma progression
L Wang, X Yi, X Xiao, Q Zheng, L Ma, B Li - Cellular & molecular biology …, 2022 - Springer
Background Hepatocellular carcinoma (HCC) is the most common type of liver cancer.
CircFUT8 has been shown to be upregulated in cancers, but its function in HCC remains …
CircFUT8 has been shown to be upregulated in cancers, but its function in HCC remains …
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling
Y Gu, Y Wang, L He, J Zhang, X Zhu, N Liu, J Wang… - Molecular cancer, 2021 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most intractable tumors in the
world due to its high rate of recurrence and heterogeneity. Liver cancer initiating cells also …
world due to its high rate of recurrence and heterogeneity. Liver cancer initiating cells also …
Circular RNA s in hepatocellular carcinoma: functions and implications
L Fu, Z Jiang, T Li, Y Hu, J Guo - Cancer Medicine, 2018 - Wiley Online Library
At present, as hotspot members of the noncoding RNA network, circular RNA s (circ RNA s)
with distinct properties and diverse pathophysiological functions are being increasingly …
with distinct properties and diverse pathophysiological functions are being increasingly …
Emerging role of circular RNAs in hepatocellular carcinoma immunotherapy
Hepatocellular carcinoma (HCC) is a highly fatal malignancy with limited therapeutic options
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …
Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma
Y Chen, Z Li, M Zhang, B Wang, J Ye, Y Zhang… - Journal of Experimental …, 2019 - Springer
Abstract Background Circular RNAs (circRNAs) have recently been shown to play important
roles in different tumors. However, their detailed roles and regulatory mechanisms in …
roles in different tumors. However, their detailed roles and regulatory mechanisms in …
The circular RNA circSKA3 binds integrin β1 to induce invadopodium formation enhancing breast cancer invasion
Metastatic cancer cells invade surrounding tissues by forming dynamic actin-based
invadopodia, which degrade the surrounding extracellular matrix and allow cancer cell …
invadopodia, which degrade the surrounding extracellular matrix and allow cancer cell …
Circular RNA—Is the Circle Perfect?
Circular RNA (circRNA) is a distinct class of non-coding RNA produced, in principle, using a
back-splicing mechanism, conserved during evolution, with increased stability and a tissue …
back-splicing mechanism, conserved during evolution, with increased stability and a tissue …
An antisense circular RNA circSCRIB enhances cancer progression by suppressing parental gene splicing and translation
J Ma, WW Du, K Zeng, N Wu, L Fang, J Lyu, AJ Yee… - Molecular Therapy, 2021 - cell.com
Circular RNAs (circRNAs) represent a large group of non-coding RNAs that are widely
detected in mammalian cells. Although most circRNAs are generated in a sense orientation …
detected in mammalian cells. Although most circRNAs are generated in a sense orientation …