[HTML][HTML] Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor …

AC Kotze, PW Hunt, P Skuce… - International Journal for …, 2014 - Elsevier
Anthelmintic resistance has a great impact on livestock production systems worldwide, is an
emerging concern in companion animal medicine, and represents a threat to our ongoing …

Understanding asthma and allergies by the lens of biodiversity and epigenetic changes

BSD Fiuza, HF Fonseca, PM Meirelles… - Frontiers in …, 2021 - frontiersin.org
Exposure to different organisms (bacteria, mold, virus, protozoan, helminths, among others)
can induce epigenetic changes affecting the modulation of immune responses and …

Proteomic Analysis of the Excretory and Secretory Proteins of Haemonchus contortus (HcESP) Binding to Goat PBMCs In Vivo Revealed Stage-Specific Binding …

JA Gadahi, S Wang, G Bo, M Ehsan, RF Yan, XK Song… - PloS one, 2016 - journals.plos.org
Haemonchus contortus is a parasitic gastrointestinal nematode, and its excretory and
secretory products (HcESPs) interact extensively with the host cells. In this study, we report …

Elucidating the molecular and developmental biology of parasitic nematodes: Moving to a multiomics paradigm

G Ma, T Wang, PK Korhonen, A Hofmann… - Advances in …, 2020 - Elsevier
In the past two decades, significant progress has been made in the sequencing, assembly,
annotation and analyses of genomes and transcriptomes of parasitic worms of …

The miRnome of Fasciola hepatica juveniles endorses the existence of a reduced set of highly divergent micro RNAs in parasitic flatworms

S Fontenla, N Dell'Oca, P Smircich, JF Tort… - International journal for …, 2015 - Elsevier
The liver fluke Fasciola hepatica is a foodborne zoonotic parasite affecting livestock
worldwide, with increasing relevance in human health. The first developmental stage that …

Recombinant proteins of helminths with immunoregulatory properties and their possible therapeutic use

LN Santos, LGC Pacheco, CS Pinheiro… - Acta tropica, 2017 - Elsevier
The inverse relationship between helminth infections and the development of immune-
mediated diseases is a cornerstone of the hygiene hypothesis and studies were carried out …

De novo transcriptome sequencing and analysis of the juvenile and adult stages of Fasciola gigantica

XX Zhang, W Cong, HM Elsheikha, GH Liu… - Infection, Genetics and …, 2017 - Elsevier
Fasciola gigantica is regarded as the major liver fluke causing fasciolosis in livestock in
tropical countries. Despite the significant economic and public health impacts of F. gigantica …

Structure-function studies of the asparaginyl-tRNA synthetase from Fasciola gigantica: understanding the role of catalytic and non-catalytic domains

V Rajendran, R Shukla, H Shukla… - Biochemical …, 2018 - portlandpress.com
The asparaginyl-tRNA synthetase (NRS) catalyzes the attachment of asparagine to its
cognate tRNA during translation. NRS first catalyzes the binding of Asn and ATP to form the …

Niche-specific gene expression in a parasitic nematode; increased expression of immunomodulators in Teladorsagia circumcincta larvae derived from host mucosa

TN McNeilly, D Frew, STG Burgess, H Wright… - Scientific reports, 2017 - nature.com
Metazoan parasites have to survive in many different niches in order to complete their life-
cycles. In the absence of reliable methods to manipulate parasite genomes and/or …

New research tools for urogenital schistosomiasis

G Rinaldi, ND Young, JD Honeycutt… - The Journal of …, 2015 - academic.oup.com
Abstract Approximately 200 000 000 people have schistosomiasis (schistosome infection).
Among the schistosomes, Schistosoma haematobium is responsible for the most infections …