Conotoxins: chemistry and biology
The venom of the marine predatory cone snails (genus Conus) has evolved for prey capture
and defense, providing the basis for survival and rapid diversification of the now estimated …
and defense, providing the basis for survival and rapid diversification of the now estimated …
Cone snails: A big store of conotoxins for novel drug discovery
Marine drugs have developed rapidly in recent decades. Cone snails, a group of more than
700 species, have always been one of the focuses for new drug discovery. These venomous …
700 species, have always been one of the focuses for new drug discovery. These venomous …
Introducing BASE: the Biomes of Australian Soil Environments soil microbial diversity database
Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
High-throughput identification of novel conotoxins from the Chinese tubular cone snail (Conus betulinus) by multi-transcriptome sequencing
Background The venom of predatory marine cone snails mainly contains a diverse array of
unique bioactive peptides commonly referred to as conopeptides or conotoxins. These …
unique bioactive peptides commonly referred to as conopeptides or conotoxins. These …
The role of defensive ecological interactions in the evolution of conotoxins
JR Prashanth, S Dutertre, AH Jin, V Lavergne… - Molecular …, 2016 - Wiley Online Library
Venoms comprise of complex mixtures of peptides evolved for predation and defensive
purposes. Remarkably, some carnivorous cone snails can inject two distinct venoms in …
purposes. Remarkably, some carnivorous cone snails can inject two distinct venoms in …
Transcriptomic and Proteomic Analysis of the Tentacles and Mucus of Anthopleura dowii Verrill, 1869
S Ramírez-Carreto, R Vera-Estrella… - Marine drugs, 2019 - mdpi.com
Sea anemone venom contains a complex and diverse arsenal of peptides and proteins of
pharmacological and biotechnological interest, however, only venom from a few species has …
pharmacological and biotechnological interest, however, only venom from a few species has …
Coordinated adaptations define the ontogenetic shift from worm-to fish-hunting in a venomous cone snail
Marine cone snails have attracted researchers from all disciplines but early life stages have
received limited attention due to difficulties accessing or rearing juvenile specimens. Here …
received limited attention due to difficulties accessing or rearing juvenile specimens. Here …
Discovery Methodology of Novel Conotoxins from Conus Species
Y Fu, C Li, S Dong, Y Wu, D Zhangsun, S Luo - Marine drugs, 2018 - mdpi.com
Cone snail venoms provide an ideal resource for neuropharmacological tools and drug
candidates discovery, which have become a research hotspot in neuroscience and new …
candidates discovery, which have become a research hotspot in neuroscience and new …
Conotoxin Diversity in Chelyconus ermineus (Born, 1778) and the Convergent Origin of Piscivory in the Atlantic and Indo-Pacific Cones
S Abalde, MJ Tenorio, CML Afonso… - Genome Biology and …, 2018 - academic.oup.com
The transcriptome of the venom duct of the Atlantic piscivorous cone species Chelyconus
ermineus (Born, 1778) was determined. The venom repertoire of this species includes at …
ermineus (Born, 1778) was determined. The venom repertoire of this species includes at …
Venomics-accelerated cone snail venom peptide discovery
SWA Himaya, RJ Lewis - International Journal of Molecular Sciences, 2018 - mdpi.com
Cone snail venoms are considered a treasure trove of bioactive peptides. Despite over 800
species of cone snails being known, each producing over 1000 venom peptides, only about …
species of cone snails being known, each producing over 1000 venom peptides, only about …