Baker's yeast as a tool for the development of antifungal kinase inhibitors—targeting protein kinase C and the cell integrity pathway

JJ Heinisch - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2005 - Elsevier
Today, the yeast Saccharomyces cerevisiae is probably the best-studied eukaryotic
organism. This review first focusses on the signaling process which is mediated by the …

The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G2 Arrest in Cryptococcus

S Altamirano, Z Li, MS Fu, M Ding, SR Fulton, JM Yoder… - Mbio, 2021 - Am Soc Microbiol
The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response
to the host lung environment that are critical for host adaptation and subsequent disease …

Cryptococcus gattii Virulence Composite: Candidate Genes Revealed by Microarray Analysis of High and Less Virulent Vancouver Island Outbreak Strains

P Ngamskulrungroj, J Price, T Sorrell, JR Perfect… - PLoS …, 2011 - journals.plos.org
Human and animal cryptococcosis due to an unusual molecular type of Cryptococcus gattii
(VGII) emerged recently on Vancouver Island, Canada. Unlike C. neoformans, C. gattii …

Dynamics of the spindle pole body of the pathogenic yeast Cryptococcus neoformans examined by freeze-substitution electron microscopy

M Yamaguchi, SK Biswas, M Ohkusu… - FEMS microbiology …, 2009 - academic.oup.com
Cryptococcus neoformans is an opportunistic human pathogen belonging to
basidiomycetous fungi and has unique properties in cell cycle progression. In the present …

New insights into the cell cycle profile of Paracoccidioides brasiliensis

AJ Almeida, M Martins, JA Carmona, LE Cano… - Fungal Genetics and …, 2006 - Elsevier
The present work focuses on the analysis of cell cycle progression of Paracoccidioides
brasiliensis yeast cells under different environmental conditions. We optimized a flow …

The single Cdk1-G1 cyclin of Cryptococcus neoformans is not essential for cell cycle progression, but plays important roles in the proper commitment to DNA …

EV Virtudazo, S Kawamoto, M Ohkusu… - FEMS yeast …, 2010 - academic.oup.com
The cell cycle pattern of the pathogenic basidiomycetous yeast Cryptococcus neoformans
differs from that of the ascomycetous budding yeast Saccharomyces cerevisiae. To clarify …

Mating differentiation in Cryptococcus neoformans is negatively regulated by the Crk1 protein kinase

KH Liu, WC Shen - Fungal genetics and biology, 2011 - Elsevier
Cryptococcus neoformans is a heterothallic basidiomycete that grows vegetatively as yeast
and filamentous hyphae are produced in the sexual state. Previous studies have shown that …

CDKA and CDKB kinases from Chlamydomonas reinhardtii are able to complement cdc28 temperature-sensitive mutants of Saccharomyces cerevisiae

M Čížková, A Pichová, M Vitova, M Hlavová… - Protoplasma, 2008 - Springer
Cyclin-dependent kinases (CDK) play a key role in coordinating cell division in all
eukaryotes. We investigated the capability of cyclin-dependent kinases CDKA and CDKB …

Alternative gene expression in type I and type II cells may enable further nuclear changes during conjugation of Blepharisma japonicum

M Sugiura, Y Tanaka, T Suzaki, T Harumoto - Protist, 2012 - Elsevier
In contrast to most ciliates, meiosis and successive nuclear changes during conjugation
occur only in heterotypic pairs in Blepharisma. It has been suggested that homotypic pairs …

[PDF][PDF] Hypoxia sensing in Cryptococcus neoformans: Biofilm-like adaptation for dormancy

Z Moranova, S Kawamoto, V Raclavsky - Biomed Pap Med Fac Univ …, 2009 - Citeseer
Background: Cryptococcus neoformans is an obligate aerobic pathogenic yeast causing
lung infection typically followed by spread to the central nervous system. During …