Current status and applications of genome-scale metabolic models
Genome-scale metabolic models (GEMs) computationally describe gene-protein-reaction
associations for entire metabolic genes in an organism, and can be simulated to predict …
associations for entire metabolic genes in an organism, and can be simulated to predict …
Synthetic biology toolbox and chassis development in Bacillus subtilis
Based on technical advances in the sequencing and synthesis of genetic components as
well as the genome, significant progress has recently been made in developing synthetic …
well as the genome, significant progress has recently been made in developing synthetic …
High‐quality genome‐scale metabolic modelling of Pseudomonas putida highlights its broad metabolic capabilities
Genome‐scale reconstructions of metabolism are computational species‐specific
knowledge bases able to compute systemic metabolic properties. We present a …
knowledge bases able to compute systemic metabolic properties. We present a …
[图书][B] Practical handbook of microbiology
LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …
knowledge and practical information about working with microorganisms. Useful to anyone …
Bacillus subtilis: from soil bacterium to super-secreting cell factory
JM van Dijl, M Hecker - Microbial cell factories, 2013 - Springer
The biotechnology industry has become a key element in modern societies. Within this
industry, the production of recombinant enzymes and biopharmaceutical proteins is of major …
industry, the production of recombinant enzymes and biopharmaceutical proteins is of major …
Large-scale reduction of the Bacillus subtilis genome: consequences for the transcriptional network, resource allocation, and metabolism
DR Reuß, J Altenbuchner, U Mäder, H Rath… - Genome …, 2017 - genome.cshlp.org
Understanding cellular life requires a comprehensive knowledge of the essential cellular
functions, the components involved, and their interactions. Minimized genomes are an …
functions, the components involved, and their interactions. Minimized genomes are an …
Quantitative prediction of genome-wide resource allocation in bacteria
A Goelzer, J Muntel, V Chubukov, M Jules, E Prestel… - Metabolic …, 2015 - Elsevier
Predicting resource allocation between cell processes is the primary step towards decoding
the evolutionary constraints governing bacterial growth under various conditions …
the evolutionary constraints governing bacterial growth under various conditions …
Developing Bacillus spp. as a cell factory for production of microbial enzymes and industrially important biochemicals in the context of systems and synthetic biology
Increasing concerns over limited petroleum resources and associated environmental
problems are motivating the development of efficient cell factories to produce chemicals …
problems are motivating the development of efficient cell factories to produce chemicals …
The Surfactin-Like Lipopeptides From Bacillus spp.: Natural Biodiversity and Synthetic Biology for a Broader Application Range
A Théatre, C Cano-Prieto, M Bartolini… - … in Bioengineering and …, 2021 - frontiersin.org
Surfactin is a lipoheptapeptide produced by several Bacillus species and identified for the
first time in 1969. At first, the biosynthesis of this remarkable biosurfactant was described in …
first time in 1969. At first, the biosynthesis of this remarkable biosurfactant was described in …
Standardizing biomass reactions and ensuring complete mass balance in genome-scale metabolic models
Motivation In a genome-scale metabolic model, the biomass produced is defined to have a
molecular weight (MW) of 1 g mmol− 1. This is critical for correctly predicting growth yields …
molecular weight (MW) of 1 g mmol− 1. This is critical for correctly predicting growth yields …