G βγ subunits from heterotrimeric G proteins perform a vast array of functions in cells with
respect to signaling, often independently as well as in concert with G α subunits. However …

Abstract Second-generation antipsychotics (SGAs), such as risperidone, clozapine and
olanzapine, are the most common drug treatments for schizophrenia. SGAs presented an …

Increased fat storage in adipose and non-adipose tissue (eg skeletal muscle) characterizes
the obese insulin resistant state. Disturbances in pathways of lipolysis may play a role in the …

This report constitutes the eighth update of the human obesity gene map, incorporating
published results up to the end of October 2001. Evidence from the rodent and human …

BACKGROUND: Risk factors for suicide are at least partially heritable and functional
polymorphisms of targeted genes have been suggested to be implicated in the …

Purpose: The aim of this study was to investigate the correlations and interactions between
the polymorphisms of insulin resistance-related genes (ADIPOQ rs2241766), inflammation …

A common C825T polymorphism in the gene GNB3, which encodes the β3 subunit of
heterotrimeric G proteins, was identified in cell lines from patients with hypertension. The …

Inflammatory bowel diseases (IBDs), including ulcerative colitis (UC) and Crohn's disease
(CD), are chronic inflammatory disorders caused by genetic influences, the immune system …

Heterotrimeric guanine-binding proteins (G proteins) transmit signals from the cell surface to
intracellular signal cascades. The β3-subunit encoded by the gene GNB3 is widely …

Obesity is the result of an imbalance between food intake and energy expenditure resulting
in the storing of energy as fat. Adipose tissue contains the largest store of energy in the body …