Buprenorphine versus methadone for the treatment of opioid dependence: a systematic review and meta-analysis of randomised and observational studies

L Degenhardt, B Clark, G Macpherson… - The Lancet …, 2023 - thelancet.com
Background Opioid dependence is associated with substantial health and social burdens,
and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for …

Medication-assisted treatment for opioid-use disorder

TS Oesterle, NJ Thusius, TA Rummans… - Mayo Clinic …, 2019 - Elsevier
Abstract The United States is in the midst of a national opioid epidemic. Physicians are
encouraged both to prevent and treat opioid-use disorders (OUDs). Although there are 3 …

Global patterns of opioid use and dependence: harms to populations, interventions, and future action

L Degenhardt, J Grebely, J Stone, M Hickman… - The Lancet, 2019 - thelancet.com
We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

The impact of relaxation of methadone take-home protocols on treatment outcomes in the COVID-19 era

O Amram, S Amiri, V Panwala, R Lutz… - The American journal …, 2021 - Taylor & Francis
ABSTRACT Background Background: In response to the COVID-19 pandemic, the US
Substance Abuse and Mental Health Services Administration (SAMHSA) allowed for an …

Changes in methadone program practices and fatal methadone overdose rates in Connecticut during COVID-19

S Brothers, A Viera, R Heimer - Journal of substance abuse treatment, 2021 - Elsevier
Background Due to the COVID-19 pandemic, the Substance Abuse and Mental Health
Services Administration (SAMHSA) has relaxed restrictions on methadone treatment in the …

Flexible buprenorphine/naloxone model of care for reducing opioid use in individuals with prescription-type opioid use disorder: an open-label, pragmatic …

D Jutras-Aswad, B Le Foll, K Ahamad… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Extensive exposure to prescription-type opioids has resulted in major harm
worldwide, calling for better-adapted approaches to opioid agonist therapy. The authors …

The methadone manifesto: treatment experiences and policy recommendations from methadone patient activists

C Simon, L Vincent, A Coulter… - … Journal of Public …, 2022 - ajph.aphapublications.org
Abuse and Mental Health Services Administration (SAMHSA) released guidance to opioid
treatment programs relaxing some of the MMT restrictions that had been in place for more …

The effectiveness of substance use interventions for homeless and vulnerably housed persons: a systematic review of systematic reviews on supervised consumption …

O Magwood, G Salvalaggio, M Beder, C Kendall… - PloS one, 2020 - journals.plos.org
Background Substance use is disproportionately high among people who are homeless or
vulnerably housed. We performed a systematic overview of reviews examining the effects of …

Recommendations for buprenorphine and methadone therapy in opioid use disorder: a European consensus

M Dematteis, M Auriacombe, O D'Agnone… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Management of patients with opioid use disorder (OUD) commonly includes
opioid agonist therapy (OAT) as a part of an integrated treatment plan. These interventions …

Provider experiences with relaxing restrictions on take-home medications for opioid use disorder during the COVID-19 pandemic: a qualitative systematic review

A Adams, S Blawatt, S MacDonald, R Finnick… - International Journal of …, 2023 - Elsevier
Background Historical restrictions on take-home medications for opioid use disorder have
generated considerable debate. The COVID-19 pandemic shifted the perceived risks and …