Bioprospecting Kluyveromyces marxianus as a Robust Host for Industrial Biotechnology

M Bilal, L Ji, Y Xu, S Xu, Y Lin, HMN Iqbal… - … in Bioengineering and …, 2022 - frontiersin.org
Kluyveromyces marxianus is an emerging non-conventional food-grade yeast that is
generally isolated from diverse habitats, like kefir grain, fermented dairy products, sugar …

Yeast-based virus-like particles as an emerging platform for vaccine development and delivery

V Srivastava, KN Nand, A Ahmad, R Kumar - Vaccines, 2023 - mdpi.com
Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …

Kluyveromyces as promising yeast cell factories for industrial bioproduction: From bio-functional design to applications

Y Qiu, P Lei, R Wang, L Sun, Z Luo, S Li, H Xu - Biotechnology Advances, 2023 - Elsevier
As the two most widely used Kluyveromyces yeast, Kluyveromyces marxianus and K. lactis
have gained increasing attention as microbial chassis in biocatalysts, biomanufacturing and …

Future perspectives on swine viral vaccines: where are we headed?

T Opriessnig, AA Mattei, AK Karuppannan… - Porcine Health …, 2021 - Springer
Deliberate infection of humans with smallpox, also known as variolation, was a common
practice in Asia and dates back to the fifteenth century. The world's first human vaccination …

High-level expression of leghemoglobin in Kluyveromyces marxianus by remodeling the heme metabolism pathway

T Tian, X Wu, P Wu, X Lu, Q Wang, Y Lin… - … in Bioengineering and …, 2024 - frontiersin.org
Soy leghemoglobin, when bound to heme, imparts a meat-like color and flavor and can
serve as a substitute for animal-derived proteins. Enhancing cellular heme synthesis …

Transfer of disulfide bond formation modules via yeast artificial chromosomes promotes the expression of heterologous proteins in Kluyveromyces marxianus

P Wu, W Mo, T Tian, K Song, Y Lyu, H Ren, J Zhou… - Mlife, 2024 - Wiley Online Library
Kluyveromyces marxianus is a food‐safe yeast with great potential for producing
heterologous proteins. Improving the yield in K. marxianus remains a challenge and …

Comparative Genomic and Transcriptomic Analysis Reveals Specific Features of Gene Regulation in Kluyveromyces marxianus

Y Yu, W Mo, H Ren, X Yang, W Lu, T Luo… - Frontiers in …, 2021 - frontiersin.org
Kluyveromyces marxianus is a promising host for producing bioethanol and heterologous
proteins. It displays many superior traits to a conventional industrial yeast species …

Investigation of Kluyveromyces marxianus as a novel host for large‐scale production of porcine parvovirus virus‐like particles

D Yang, L Chen, J Duan, Y Yu, J Zhou, H Lu - Microbial Cell Factories, 2021 - Springer
Abstract Background Porcine Parvovirus (PPV) is a Parvovirinae virus that can cause
embryonic and fetal loss and death and mummification in affected fetal pigs. Unlike …

Contribution of yeast models to virus research

R Sahaya Glingston, J Yadav, J Rajpoot… - Applied Microbiology …, 2021 - Springer
Time and again, yeast has proven to be a vital model system to understand various crucial
basic biology questions. Studies related to viruses are no exception to this. This simple …

Synthesis of polyketides from low cost substrates by the thermotolerant yeast Kluyveromyces marxianus

TL McTaggart, D Bever, S Bassett… - Biotechnology and …, 2019 - Wiley Online Library
Kluyveromyces marxianus is a promising nonconventional yeast for biobased chemical
production due to its rapid growth rate, high TCA cycle flux, and tolerance to low pH and …