BACKGROUND Although chromosomal mosaicism in human preimplantation embryos has
been described for almost two decades, its exact prevalence is still unknown. The …

Preimplantation genetic diagnosis (PGD) was introduced at the beginning of the 1990s as
an alternative to prenatal diagnosis, to prevent termination of pregnancy in couples with a …

Among the many educational materials produced by the European Society of Human
Reproduction and Embryology (ESHRE) are guidelines. ESHRE guidelines may be …

BACKGROUND Recent studies have suggested that biopsy of several trophectoderm (TE)
cells from blastocysts followed by comparative genomic hybridization (CGH) analysis might …

The first edition of the Textbook of Assisted Reproductive Techniques was published in
2001. As the textbook now enters its sixth edition, some 45 years since the birth of Louise …

This chapter is an update to our previous reviews on this subject. 1, 2 In those reviews we
explained that when an in vitro fertilization (IVF) clinic successfully attains a high …

Human reproduction is remarkably inefficient; nearly 70% of human conceptions do not
survive to live birth. Spontaneous fetal aneuploidy is the most common cause for …

For the last 20 years, preimplantation genetic diagnosis (PGD) has been mostly performed
on cleavage stage embryos after the biopsy of 1–2 cells and PCR and FISH have been used …

We have used multicolour fluorescent in situ hybridisation (FISH) with DNA probes for
chromosomes X, Y and 1 to analyse spare untransferred cleavage-stage embryos after …

BACKGROUND: In order to assess the frequency of aneuploidy and mosaicism in embryos
obtained from IVF patients aged< 38 years, preimplantation genetic screening (PGS) was …