What is intervertebral disc degeneration, and what causes it?
MA Adams, PJ Roughley - Spine, 2006 - journals.lww.com
Study Design. Review and reinterpretation of existing literature. Objective. To suggest how
intervertebral disc degeneration might be distinguished from the physiologic processes of …
intervertebral disc degeneration might be distinguished from the physiologic processes of …
Reciprocal interplay between fibrillar collagens and collagen-binding integrins: implications in cancer progression and metastasis
Cancers are complex ecosystems composed of malignant cells embedded in an intricate
microenvironment made of different non-transformed cell types and extracellular matrix …
microenvironment made of different non-transformed cell types and extracellular matrix …
[HTML][HTML] Cartilage and meniscal T2 relaxation time as non-invasive biomarker for knee osteoarthritis and cartilage repair procedures
T Baum, GB Joseph, DC Karampinos… - Osteoarthritis and …, 2013 - Elsevier
Objective The purpose of this work was to review the current literature on cartilage and
meniscal T2 relaxation time. Methods Electronic searches in PubMed were performed to …
meniscal T2 relaxation time. Methods Electronic searches in PubMed were performed to …
[HTML][HTML] Depth-wise progression of osteoarthritis in human articular cartilage: investigation of composition, structure and biomechanics
S Saarakkala, P Julkunen, P Kiviranta… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVE: Osteoarthritis (OA) is characterized by the changes in structure and
composition of articular cartilage. However, it is not fully known, what is the depth-wise …
composition of articular cartilage. However, it is not fully known, what is the depth-wise …
[HTML][HTML] Quantitative MRI techniques of cartilage composition
SJ Matzat, J van Tiel, GE Gold… - Quantitative imaging in …, 2013 - ncbi.nlm.nih.gov
Due to aging populations and increasing rates of obesity in the developed world, the
prevalence of osteoarthritis (OA) is continually increasing. Decreasing the societal and …
prevalence of osteoarthritis (OA) is continually increasing. Decreasing the societal and …
[HTML][HTML] The relation between the biochemical composition of knee articular cartilage and quantitative MRI: a systematic review and meta-analysis
KS Emanuel, LJ Kellner, MJM Peters… - Osteoarthritis and …, 2022 - Elsevier
Objective Early and non-invasive detection of osteoarthritis (OA) is required to enable early
treatment and monitoring of interventions. Some of the earliest signs of OA are the change in …
treatment and monitoring of interventions. Some of the earliest signs of OA are the change in …
T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients—a 3.0-Tesla MRI study
To assess the degree of focal cartilage abnormalities in physically active and sedentary
healthy subjects as well as in patients with early osteoarthritis (OA).(2) To determine the …
healthy subjects as well as in patients with early osteoarthritis (OA).(2) To determine the …
Collagen morphology and texture analysis: from statistics to classification
In this study we present an image analysis methodology capable of quantifying
morphological changes in tissue collagen fibril organization caused by pathological …
morphological changes in tissue collagen fibril organization caused by pathological …
MR imaging of articular cartilage physiology
Osteoarthritis (OA) has become the most prevalent chronic disease of the elderly (1, 2) and
is an important cause of disability in our society with increasing incidence not only in the US …
is an important cause of disability in our society with increasing incidence not only in the US …
[HTML][HTML] Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years …
OBJECTIVE: The purpose of this study is to determine whether the mean and heterogeneity
of magnetic resonance (MR) knee cartilage T2 relaxation time measurements at baseline …
of magnetic resonance (MR) knee cartilage T2 relaxation time measurements at baseline …