Cholangiocarcinoma 2020: the next horizon in mechanisms and management

JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

Liver resection and transplantation for intrahepatic cholangiocarcinoma

V Mazzaferro, A Gorgen, S Roayaie, MD dit Busset… - Journal of …, 2020 - Elsevier
The incidence of intrahepatic cholangiocarcinoma (iCCA) is increasing worldwide. Although
several advances have been made in the past decades to better understand this complex …

AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma

CL Bowlus, L Arrivé, A Bergquist, M Deneau… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Very early recurrence after liver resection for intrahepatic cholangiocarcinoma: considering alternative treatment approaches

DI Tsilimigras, K Sahara, L Wu, D Moris… - JAMA …, 2020 - jamanetwork.com
Importance Although surgery offers the best chance of a potential cure for patients with
localized, resectable intrahepatic cholangiocarcinoma (ICC), prognosis of patients remains …

Genetic determinants of outcome in intrahepatic cholangiocarcinoma

T Boerner, E Drill, LM Pak, B Nguyen, CS Sigel… - …, 2021 - Wiley Online Library
Background and Aim Genetic alterations in intrahepatic cholangiocarcinoma (iCCA) are
increasingly well characterized, but their impact on outcome and prognosis remains …

Liver transplantation for locally advanced intrahepatic cholangiocarcinoma treated with neoadjuvant therapy: a prospective case-series

KE Lunsford, M Javle, K Heyne, RT Shroff… - The lancet …, 2018 - thelancet.com
Background At present, intrahepatic cholangiocarcinoma is a contraindication for liver
transplantation. However, previous studies in this field did not preselect patients on the basis …

Liver transplantation for intrahepatic cholangiocarcinoma: ready for prime time?

G Sapisochin, T Ivanics, J Heimbach - Hepatology, 2022 - Wiley Online Library
Cholangiocarcinoma (CCA) represents the second‐most common primary liver malignancy
after HCC and has risen in incidence globally in the past decades. Intrahepatic …

A radiomics approach to predict lymph node metastasis and clinical outcome of intrahepatic cholangiocarcinoma

GW Ji, FP Zhu, YD Zhang, XS Liu, FY Wu, K Wang… - European …, 2019 - Springer
Objectives This study was conducted in order to establish and validate a radiomics model for
predicting lymph node (LN) metastasis of intrahepatic cholangiocarcinoma (IHC) and to …

Recurrence patterns and timing courses following curative-intent resection for intrahepatic cholangiocarcinoma

LS Hu, XF Zhang, M Weiss, I Popescu… - Annals of surgical …, 2019 - Springer
Background Recurrence of intrahepatic cholangiocarcinoma (ICC) after curative resection is
common. Objective The aim of this study was to investigate the patterns, timing and risk …

AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/Smad3 pathway

L Deng, W Bao, B Zhang, S Zhang, Z Chen, X Zhu… - Cell Death & …, 2023 - nature.com
Intrahepatic cholangiocarcinoma (ICC) is a primary liver malignancy and is characterized by
highly aggressive and malignant biological behavior. Currently, effective treatment …