Roles of HMGA proteins in cancer

A Fusco, M Fedele - Nature Reviews Cancer, 2007 - nature.com
The high mobility group A (HMGA) non-histone chromatin proteins alter chromatin structure
and thereby regulate the transcription of several genes by either enhancing or suppressing …

Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins

M Bustin - Molecular and cellular biology, 1999 - Taylor & Francis
The orderly progression of most DNA-related activities such as transcription, replication,
recombination, and repair involves changes in the structure of the DNA and in the …

Updates on cytogenetics and molecular genetics of bone and soft tissue tumors:: Ewing sarcoma and peripheral primitive neuroectodermal tumors

AA Sandberg, JA Bridge - Cancer genetics and cytogenetics, 2000 - Elsevier
Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

Fine-needle aspiration biopsy of the thyroid

A Belfiore, GL La Rosa - Endocrinology and Metabolism Clinics, 2001 - endo.theclinics.com
After fine-needle aspiration biopsy (FNAB) of the thyroid was first described in 1948, 1 7 it
was mainly developed by Scandinavian researchers. 80, lZ7 In the early 1970s, it was used …

[HTML][HTML] Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer

R Sgarra, A Rustighi, MA Tessari, J Di Bernardo… - FEBS letters, 2004 - Elsevier
The structural characteristics of the three nuclear phosphoproteins of the high mobility group
A family are outlined and related to their participation in chromatin structure alteration in …

HMGA2 overexpression in non‐small cell lung cancer

B Meyer, S Loeschke, A Schultze… - … in cooperation with …, 2007 - Wiley Online Library
Lung cancer is still the leading cause of death from cancer worldwide primarily because of
the fact that most lung cancers are diagnosed at advanced stages. Overexpression of the …

Architectural transcription factor HMGI (Y) promotes tumor progression and mesenchymal transition of human epithelial cells

R Reeves, DD Edberg, Y Li - Molecular and cellular biology, 2001 - Taylor & Francis
Numerous studies have demonstrated that overexpression or aberrant expression of the
HMGI (Y) family of architectural transcription factors is frequently associated with both …

Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas

M Fedele, S Battista, L Kenyon, G Baldassarre… - Oncogene, 2002 - nature.com
Overexpression of the HMGA2 gene is a common feature of neoplastic cells both in
experimental and human models. Intragenic and extragenic HMGA2 rearrangements …

Characterization of thyroid 'follicular neoplasms' in fine-needle aspiration cytological specimens using a panel of immunohistochemical markers: a proposal for clinical …

E Saggiorato, R De Pompa, M Volante… - Endocrine-related …, 2005 - erc.bioscientifica.com
The distinction of benign from malignant follicular thyroid neoplasms remains a difficult task
in diagnostic fine-needle aspiration cytology, and some discrepant results have been …

The high mobility group A1 (HMGA1) transcriptome in cancer and development

TF Sumter, L Xian, T Huso, M Koo… - Current molecular …, 2016 - ingentaconnect.com
Background & Objectives: Chromatin structure is the single most important feature that
distinguishes a cancer cell from a normal cell histologically. Chromatin remodeling proteins …