Patient-reported outcomes (PROs) in COPD clinical trials: trends and gaps

N Afroz, FS Gutzwiller, AJ Mackay… - … Journal of Chronic …, 2020 - Taylor & Francis
Key characteristics of chronic obstructive pulmonary disease (COPD) that significantly affect
health-related quality of life (HRQoL) include chest symptoms, dyspnea, cough, sputum …

Chronic obstructive pulmonary disease individualized therapy: tailored approach to symptom management

D Singh, M Miravitlles, C Vogelmeier - Advances in therapy, 2017 - Springer
Chronic obstructive pulmonary disease (COPD) is associated with high morbidity and
mortality. COPD is typified by persistent, progressive airflow limitation and a range of …

Adherence to inhaled therapies of COPD patients from seven Latin American countries: The LASSYC study

M Montes de Oca, A Menezes, FC Wehrmeister… - PloS one, 2017 - journals.plos.org
Background This study assessed the adherence profiles to inhaled therapies and the
agreement between two patient self-report adherence methods in stable COPD lpatients …

AMPLIFY: a randomized, phase III study evaluating the efficacy and safety of aclidinium/formoterol vs monocomponents and tiotropium in patients with moderate-to …

S Sethi, E Kerwin, H Watz, GT Ferguson… - … Journal of Chronic …, 2019 - Taylor & Francis
Background AMPLIFY assessed the efficacy and safety of aclidinium bromide/formoterol
fumarate (AB/FF) vs its monocomponents and tiotropium (TIO) in patients with moderate-to …

[HTML][HTML] The variability of respiratory symptoms and associated factors in COPD

M Miravitlles, JL Izquierdo, C Esquinas, M Pérez… - Respiratory …, 2017 - Elsevier
Few studies have investigated the variability of COPD-related symptoms or factors related to
symptom variability. This observational, prospective, multicentre study was conducted to …

Importance of the relationship between symptoms and self-reported physical activity level in stable COPD based on the results from the SPACE study

F Mihaltan, Y Adir, A Antczak, K Porpodis… - Respiratory …, 2019 - Springer
Background The burden of symptoms and risk of exacerbations are the main drivers of the
overall assessment of the Chronic Obstructive Pulmonary Disease (COPD) and the …

[HTML][HTML] A randomised double-blind, placebo-controlled, long-term extension study of the efficacy, safety and tolerability of fixed-dose combinations of aclidinium …

A D'Urzo, S Rennard, E Kerwin, JF Donohue, A Lei… - Respiratory …, 2017 - Elsevier
Introduction Aclidinium bromide/formoterol fumarate (AB/FF) 400/12 μg efficacy and safety
was demonstrated in two 6-month Phase III studies (AUGMENT and ACLIFORM) and a 12 …

[HTML][HTML] The burden of cough and phlegm in people with COPD: a COPD patient-powered research network study

R Choate, CB Pasquale, NA Parada… - … Diseases: Journal of …, 2020 - ncbi.nlm.nih.gov
Rationale: Cough and phlegm are common symptoms of chronic obstructive pulmonary
disease (COPD) and may significantly affect quality of life. This study assessed the burden of …

Characteristics of COPD patients managed in respiratory medicine departments in Spain, according to GOLD groups and GesEPOC clinical phenotypes

JL Izquierdo, M Miravitlles, C Esquinas, M Pérez… - Archivos de …, 2018 - Elsevier
Introduction The objective of this study was to analyze the clinical characteristics of COPD
patients attending general respiratory clinics, adherence to clinical guidelines, classification …

Cognitive interviewing in patient-reported outcome measures: A systematic review of methodological processes.

J Wright, N Moghaddam, DL Dawson - Qualitative Psychology, 2021 - psycnet.apa.org
Abstract Patient Reported Outcome Measures (PROMs) are standardized surveys assessing
functional status, health, and wellbeing. Contemporary movement toward the evaluation of …