High uric acid (UA) levels can cause gout, urolithiasis and acute and chronic nephropathy,
all of which are due to the deposit of urate crystals. There is also increasing evidence of …

The effect of nutrition and dietary supplements on the course of multiple sclerosis (MS) is a
topic of great interest to both patients and clinicians. In particular, vitamin D status has been …

Even with the evolution of chemotherapeutic procedures and agents, chemotherapy may
cause certain side effects that impair the patients' quality of life. The aim of this review is to …

Multiple sclerosis (MS) is a neuroinflammatory disease with limited therapeutic effects,
eventually developing into handicap. Seeking novel therapeutic strategies for MS is timely …

Uric acid (UA) is considered to be one of the most important antioxidants in the blood. While
high UA levels are found in many disease states, low UA levels are reported in many …

Active autophagy/mitophagy could mediate neurodegeneration and motor disabilities in
multiple sclerosis (MS). Mitochondrial recruitment of dynamin-related protein 1 (Drp1) is a …

OBJECTIVES: In this study, the concentrations of uric acid, purine profile and creatinine in
samples of cerebrospinal fluid and serum of multiple sclerosis (MS) patients were measured …

Oxidative stress and neuroinflammation have a role in the pathogenesis of multiple sclerosis
(MS) and in depression. Fatigue is the most disabling symptom in patients with MS and …

Reactive oxygen species (ROS) play an important role in various events underlying multiple
sclerosis pathology. In the initial phase of lesion formation, ROS are known to mediate the …

Multiple sclerosis (MS) is a progressive demyelinating process considered as an
autoimmune disease, although the causes of this pathology have not been yet fully …