[HTML][HTML] Environmental exposures to cadmium and lead as potential causes of eye diseases

M Ebrahimi, M Ebrahimi, JE Vergroesen… - Journal of Trace …, 2023 - Elsevier
Humans are exposed to cadmium and lead in various regions of the world daily due to
industrial development and climate change. Increasing numbers of preclinical and clinical …

Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis

C Wu, H Liu, Z Zhan, X Zhang, M Zhang, J You… - Scientific Reports, 2024 - nature.com
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital facial
malformation with a complex, incompletely understood origin. Long noncoding RNAs …

Expression Analysis of RbBP6 in human cancers: a Prospective biomarker

Z Mbita, R Hull, M Mbele, T Makhafola… - Anti-Cancer …, 2019 - journals.lww.com
Abstract Retinoblastoma binding protein 6 (RBBP6) is a cancer-related protein that has
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …

Identification of immunogenic proteins of the cysticercoid of Hymenolepis diminuta

A Sulima, J Bień, K Savijoki, A Näreaho, R Sałamatin… - Parasites & vectors, 2017 - Springer
Background A wide range of molecules are used by tapeworm metacestodes to establish
successful infection in the hostile environment of the host. Reports indicating the proteins in …

Non‐canonical proline‐tyrosine interactions with multiple host proteins regulate Ebola virus infection

J Batra, H Mori, GI Small, M Anantpadma… - The EMBO …, 2021 - embopress.org
The Ebola virus VP30 protein interacts with the viral nucleoprotein and with host protein
RBBP6 via PPxPxY motifs that adopt non‐canonical orientations, as compared to other …

Genetic predictors of hippocampal subfield volume in PTSD cases and trauma-exposed controls

RA Morey, ME Garrett, JS Stevens… - European Journal of …, 2020 - Taylor & Francis
Behavioural, structural, and functional neuroimaging have implicated the hippocampus as a
critical brain region in posttraumatic stress disorder (PTSD) pathogenesis. Recent work in a …

Dysregulation of alternative splicing contributes to multiple myeloma pathogenesis

S Song, W Zhang, Q Li, Z Wang, Q Su, X Zhang… - British Journal of …, 2023 - nature.com
Background Dysregulation of alternative splicing (AS) triggers many tumours, understanding
the roles of splicing events during tumorigenesis would open new avenues for therapies and …

Methyl pyruvate protects a normal lung fibroblast cell line from irinotecan-induced cell death: Potential use as adjunctive to chemotherapy

B Monchusi, M Ntwasa - PloS one, 2017 - journals.plos.org
The Warburg Effect, characterized by increased rate of glycolysis even under normoxic
conditions, is one of the hallmarks of cancer. Relatively lower oxidative phosphorylation …

Knockdown of RBBP6 enhances radiosensitivity of gastric cancer cells through p53 pathway

M Bi, J Sun, F Wang, S Li - Molecular & Cellular Toxicology, 2022 - Springer
Background Radiotherapy is regarded as commonly standard-of-care for the treatment of
patients with gastric cancer. However, the resistance to radiotherapy impedes the efficiency …

Downregulation of RBBP6 variant 1 during arsenic trioxide-mediated cell cycle arrest and curcumin-induced apoptosis in MCF-7 breast cancer cells

L Makgoo, K Laka, Z Mbita - Future Science OA, 2019 - Taylor & Francis
Aim: To determine the expression patterns of the RBBP6 spliced variants during arsenic
trioxide-mediated cell cycle arrest and curcumin-induced apoptosis in MCF-7 cells. Materials …