Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as
shaping cancer immunosurveillance and response to immunotherapy. Our understanding of …

Blautia is a genus of anaerobic bacteria with probiotic characteristics that occur widely in the
feces and intestines of mammals. Based on phenotypic and phylogenetic analyses, some …

Anti-CD19 chimeric antigen receptor (CAR) T cell therapy has led to unprecedented
responses in patients with high-risk hematologic malignancies. However, up to 60% of …

Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …

Background Relationships between microbiota composition and clinical outcomes after
allogeneic hematopoietic-cell transplantation have been described in single-center studies …

The microbiome is receiving significant attention given its influence on a host of human
diseases including cancer. Its role in response to cancer treatment is becoming increasingly …

We report the first case series of immune checkpoint inhibitors (ICI)-associated colitis
successfully treated with fecal microbiota transplantation, with reconstitution of the gut …