Pasteurella multocida was first shown to be the causative agent of fowl cholera by Louis
Pasteur in 1881. Since then, this Gram-negative bacterium has been identified as the …

The molecular mechanisms used by the gonococcus to initiate infection exhibit gender
specificity. The clinical presentations of disease are also strikingly different upon comparison …

Neisseria meningitidis binds factor H (fH), a key regulator of the alternative complement
pathway. A∼ 29 kD fH-binding protein expressed in the meningococcal outer membrane …

Complement forms an important arm of innate immunity against invasive meningococcal
infections. Binding of the alternative complement pathway inhibitor factor H (fH) to fH-binding …

Meningococcal infection remains a worldwide health problem, and understanding the
mechanisms by which Neisseria meningitidis evades host innate and acquired immunity is …

Major pathogenic clonal complexes (cc) of Neisseria meningitidis differ substantially in their
point prevalence among healthy carriers. We show that frequently carried pathogenic cc (eg …

Complement forms a key arm of innate immune defenses against gonococcal infection.
Sialylation of gonococcal lipo-oligosaccharide, or expression of porin 1A (Por1A) protein …

Neisseria meningitidis (meningococcus) is an important cause of meningitis and sepsis.
Currently, there is no effective vaccine against serogroup B meningococcal infection. Host …

The capacity of Neisseria gonorrhoeae to cause disseminated gonococcal infection requires
that such strains resist the bactericidal action of normal human serum. The bactericidal …

Acute bacterial meningitis is a life-threatening disease in humans. Discussed as entry sites
for pathogens into the brain are the blood-brain and the blood-cerebrospinal fluid barrier …