The genetic landscape of substance use disorders
Substance use disorders represent a significant public health concern with considerable
socioeconomic implications worldwide. Twin and family-based studies have long …
socioeconomic implications worldwide. Twin and family-based studies have long …
Considerations for the application of polygenic scores to clinical care of individuals with substance use disorders
Substance use disorders (SUDs) are highly prevalent and associated with excess morbidity,
mortality, and economic costs. Thus, there is considerable interest in the early identification …
mortality, and economic costs. Thus, there is considerable interest in the early identification …
The relationship between alcohol-and sleep-related traits: results from polygenic risk score and Mendelian randomization analyses
Study objectives We investigated whether genetic risk for insomnia and sleep duration
abnormalities are associated with AUD and alcohol consumption. We also evaluated the …
abnormalities are associated with AUD and alcohol consumption. We also evaluated the …
Next‐generation biomarkers for alcohol consumption and alcohol use disorder diagnosis, prognosis, and treatment: A critical review
This critical review summarizes the current state of omics‐based biomarkers in the alcohol
research field. We first provide definitions and background information on alcohol and …
research field. We first provide definitions and background information on alcohol and …
Predicting Heterogeneity in Patient Response to Morphine Treatment for Neonatal Opioid Withdrawal Syndrome
D Smolyak, EM Humphries, A Parikh… - Clinical …, 2023 - Wiley Online Library
Infants with neonatal opioid withdrawal syndrome commonly receive morphine treatment to
manage their withdrawal signs. However, the effectiveness of this pharmacotherapy in …
manage their withdrawal signs. However, the effectiveness of this pharmacotherapy in …