[HTML][HTML] Cutting-edge ai technologies meet precision medicine to improve cancer care

PC Lin, YS Tsai, YM Yeh, MR Shen - Biomolecules, 2022 - mdpi.com
To provide precision medicine for better cancer care, researchers must work on clinical
patient data, such as electronic medical records, physiological measurements, biochemistry …

[HTML][HTML] The mutational profile of immune surveillance genes in diagnostic and refractory/relapsed DLBCLs

M Nesic, M Sønderkær, RF Brøndum, TC El-Galaly… - BMC cancer, 2021 - Springer
Background Diffuse large B-cell lymphoma (DLBCL) is the most frequent lymphoid
neoplasm among adults, and approximately 30–40% of patients will experience relapse …

[HTML][HTML] Optimization of preanalytical variables for cfDNA processing and detection of ctDNA in archival plasma samples

M Nesic, JS Bødker, SK Terp, K Dybkær - BioMed Research …, 2021 - hindawi.com
DNA released from cells into the peripheral blood is known as cell-free DNA (cfDNA),
representing a promising noninvasive source of biomarkers that could be utilized to manage …

[HTML][HTML] Patient-reported outcomes in patients with hematological relapse or progressive disease: a longitudinal observational study

M Sommer, LK Nielsen, LB Nielsen… - Health and Quality of …, 2021 - Springer
Background Patients with hematological cancer who experience relapse or progressive
disease often face yet another line of treatment and continued mortality risk that could …

Feasibility and early clinical impact of precision medicine for late-stage cancer patients in a regional public academic hospital

M Ladekarl, AK Nøhr, M Sønderkær, SC Dahl… - Acta …, 2023 - Taylor & Francis
Aim Our goal was to describe a precision medicine program in a regional academic hospital,
characterize features of included patients and present early data on clinical impact …

Software Workflows and Infrastructures for Precision Oncology

W Osman, A Laganà - Computational Methods for Precision Oncology, 2022 - Springer
Precision oncology mainly relies on genetic and molecular patient profiling from high-
throughput sequencing data. The necessity to process and analyze large volumes of data …

Implementing a data infrastructure for precision oncology projects leveraging REDCap

C Vesteghem, SC Dahl, RF Brøndum, M Sønderkær… - medRxiv, 2022 - medrxiv.org
Objectives To facilitate clinical implementation and research in precision oncology, notably
the pairing of patients, variants and treatments to identify candidates for clinical trials, we …

[HTML][HTML] An Aggressive Course of Transformed Splenic Diffuse Red Pulp Small B-Cell Lymphoma With Novel Somatic Loss-of-Function Mutation in RB1

LM Christensen, MT Severinsen, P Katoch… - Journal of …, 2023 - ncbi.nlm.nih.gov
Splenic diffuse red pulp small B-cell lymphoma (SDRPL) is an extremely rare B-cell
lymphoma. The disease is typically indolent and treatment with splenectomy usually results …

Direct costs of antineoplastic and supportive treatment for progressive multiple myeloma in a tax-based health system

RF Brøndum, AS Vestergaard, L Børty… - Future …, 2021 - Taylor & Francis
Aim: To estimate current real-world costs of drugs and supportive care for the treatment of
multiple myeloma in a tax-based health system. Methods: Forty-one patients were included …

[PDF][PDF] The role of genetic alterations and immune surveillance in diffuse large B-cell lymphoma

M Nesic - 2021 - vbn.aau.dk
This thesis presents the work carried out from February 2017 to February 2021 at the
Department of Hematology, Aalborg University Hospital, and the Department of Clinical …